J Korean Assoc Oral Maxillofac Surg.  2016 Feb;42(1):38-42. 10.5125/jkaoms.2016.42.1.38.

Histologic analysis of resorbable blasting media surface implants retrieved from humans: a report of two cases

• Jeong KI
• Kim YK
• Moon SW
• Kim SG
• Lim SC
• Yun PY

• KMID: 2189410
• DOI: http://doi.org/10.5125/jkaoms.2016.42.1.38

Abstract

The purpose of this study is to evaluate the degree of osseointegration of resorbable blasting media (RBM) surface implants retrieved from humans. Three implants in the mandibular molar region that were surface-treated with RBM were retrieved from two patients. The implants were used to manufacture specimens in order to measure the bone-implant contact (BIC) ratio. The BIC ratios of the three implants were found to be an average of 69.0%+/-9.1%. In conclusion, that RBM surface implants are integrated into the host environment with histological significance and the BIC ratio of the RBM surface-treated implant was not significantly different from that of other surface-treated implants.

Keyword

Dental implants; Removal

MeSH Terms

Dental Implants
Humans*
Molar
Osseointegration
Dental Implants

Figure

• 

  Fig. 1 Bone resorption progressed from upper first thread of #36 implant and second thread of #37 implant.

• 

  Fig. 2 Malposed implant was observed. Implant prosthesis was retrieved.

• 

  Fig. 3 A. Overview of a histological section obtained from the retrieved implant. No resorption of the coronal bone is present and no infrabony pockets are present (Villanueva osteochrome bone staining, ×12.5). B. Newly formed bone can be observed around the implant. The dark line is due to trabeculae of newly formed bone. Gaps around the implant are defects created during specimen production (Villanueva osteochrome bone stain, ×40).

• 

  Fig. 4 A. Overview of a histologic section obtained from the retrieved implant. Bone resorption can be observed around the implant. Whitish artifact is due to trabeculae of newly formed bone. Gaps around the implant are defects created during specimen production (Villanueva osteochrome bone staining, ×12.5). B. Newly formed bone and pre-existing bone can be observed around the implant. The grayish/whitish translucent area on the right side is an artifact created by trabeculae of newly formed bone (Villanueva osteochrome bone staining, ×40).

• 

  Fig. 5 A. At low magnification, loose contact between the implant and bone can be observed. There are gaps and fibrous tissue at the implant-bone interface (Villanueva osteochrome bone staining, ×12.5). B. At higher magnification, newly formed bone can be observed between fixture threads. Farthest to the right, the red-stained area indicates newly formed bone. The orange-stained area between the fixture and newly formed bone indicates connective tissue (Villanueva osteochrome bone staining, ×40).

Reference

1. Albrektsson T. Direct bone anchorage of dental implants. J Prosthet Dent. 1983; 50:255–261. PMID: 6352912.

2. Eriksson C, Lausmaa J, Nygren H. Interactions between human whole blood and modified TiO2-surfaces: influence of surface topography and oxide thickness on leukocyte adhesion and activation. Biomaterials. 2001; 22:1987–1996. PMID: 11426876.

3. Tortamano Neto P, Camargo LO. Prospective clinical evaluation of dental implants with sand-blasted, large-grit, acid-etched surfaces loaded 6 weeks after surgery. Quintessence Int. 2004; 35:717–722. PMID: 15470995.

4. Romanos GE, Testori T, Degidi M, Piattelli A. Histologic and histomorphometric findings from retrieved, immediately occlusally loaded implants in humans. J Periodontol. 2005; 76:1823–1832. PMID: 16274300.

5. Scarano A, Degidi M, Iezzi G, Petrone G, Piattelli A. Correlation between implant stability quotient and bone-implant contact: a retrospective histological and histomorphometrical study of seven titanium implants retrieved from humans. Clin Implant Dent Relat Res. 2006; 8:218–222. PMID: 17100747.

6. Degidi M, Piattelli A, Shibli JA, Perrotti V, Iezzi G. Bone formation around immediately loaded and submerged dental implants with a modified sandblasted and acid-etched surface after 4 and 8 weeks: a human histologic and histomorphometric analysis. Int J Oral Maxillofac Implants. 2009; 24:896–901. PMID: 19865630.

7. Rahbek O, Kold S, Bendix K, Overgaard S, Søballe K. Superior sealing effect of hydroxyapatite in porous-coated implants: experimental studies on the migration of polyethylene particles around stable and unstable implants in dogs. Acta Orthop. 2005; 76:375–385. PMID: 16156466.

8. Cook SD, Kay JF, Thomas KA, Jarcho M. Interface mechanics and histology of titanium and hydroxylapatite-coated titanium for dental implant applications. Int J Oral Maxillofac Implants. 1987; 2:15–22. PMID: 3032787.

9. Brunel G, Armand S, Miller N, Rue J. Histologic analysis of a fractured implant: a case report. Int J Periodontics Restorative Dent. 2000; 20:520–526. PMID: 11203589.

10. de Lange G, Tadjoedin E. Fate of the HA coating of loaded implants in the augmented sinus floor: a human case study of retrieved implants. Int J Periodontics Restorative Dent. 2002; 22:287–296. PMID: 12186351.

11. Sul YT. The significance of the surface properties of oxidized titanium to the bone response: special emphasis on potential biochemical bonding of oxidized titanium implant. Biomaterials. 2003; 24:3893–3907. PMID: 12834584.

12. Ivanoff CJ, Widmark G, Johansson C, Wennerberg A. Histologic evaluation of bone response to oxidized and turned titanium micro-implants in human jawbone. Int J Oral Maxillofac Implants. 2003; 18:341–348. PMID: 12814308.

13. Rocci A, Martignoni M, Burgos PM, Gottlow J, Sennerby L. Histology of retrieved immediately and early loaded oxidized implants: light microscopic observations after 5 to 9 months of loading in the posterior mandible. Clin Implant Dent Relat Res. 2003; 5(Suppl 1):88–98. PMID: 12691655.

14. Davies JE. Mechanisms of endosseous integration. Int J Prosthodont. 1998; 11:391–401. PMID: 9922731.

15. Bugea C, Luongo R, Di Iorio D, Cocchetto R, Celletti R. Bone contact around osseointegrated implants: histologic analysis of a dual-acid-etched surface implant in a diabetic patient. Int J Periodontics Restorative Dent. 2008; 28:145–151. PMID: 18546810.

16. Iezzi G, Scarano A, Mangano C, Cirotti B, Piattelli A. Histologic results from a human implant retrieved due to fracture 5 years after insertion in a sinus augmented with anorganic bovine bone. J Periodontol. 2008; 79:192–198. PMID: 18166111.

17. Testori T, Szmukler-Moncler S, Francetti L, Del Fabbro M, Scarano A, Piattelli A, et al. Immediate loading of Osseotite implants: a case report and histologic analysis after 4 months of occlusal loading. Int J Periodontics Restorative Dent. 2001; 21:451–459. PMID: 11693238.

18. Nkenke E, Hahn M, Weinzierl K, Radespiel-Tröger M, Neukam FW, Engelke K. Implant stability and histomorphometry: a correlation study in human cadavers using stepped cylinder implants. Clin Oral Implants Res. 2003; 14:601–609. PMID: 12969364.

19. Kim YK, Kim SG, Kim JH, Yi YJ, Yun PY. Prospective study of tapered resorbable blasting media surface implant stability in the maxillary posterior area. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012; 114:e19–e24. PMID: 22732852.