J Korean Neurosurg Soc.  1993 Feb;22(2):188-198.

Medulloblastoma:Outcome and Prognostic Factors

• Yoon SH
• Lee KS
• Park YG
• Choi JU
• Chung SS
• Lee KC

Abstract

43 patients with medulloblastoma of the posterior fossa were treated at the Department of Neurosurgery Yonsei University College of Medicine from 1981 to 1991. Major treatment were surgery, irradiation, chemotherapy or combination. Mean follow-up was 30 months(range, 1 to 120 months). Kaplan-Meier actuarial survival for all patients 59% at 3 years. Disease free survival was 53% at 3 years. Radiation and treatment period(before 1986 vs after 1986) affected outcome significantly. But other prognosic factors such as age, extent of surgical resection and chemotherapy did not affect outcome statistically. Follow-up more than 3 years showed very low recurrence rate.

Keyword

Brain tumor; Medulloblastoma; Radiation therapy; Chemotherapy; Prognosis

MeSH Terms

Brain Neoplasms
Disease-Free Survival
Drug Therapy
Follow-Up Studies
Humans
Medulloblastoma
Neurosurgery
Prognosis
Recurrence