J Korean Neurol Assoc.
2013 Aug;31(3):199-202.
Epstein-Barr Virus Brainstem Encephalitis With Anti-N-methyl-D-aspartate Receptor Antibodies
- Affiliations
-
- 1Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. stemcell.snu@gmail.com
- 2Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
- 3Department of Neurology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.
Abstract
- The neurological manifestations caused by Epstein-Barr virus (EBV) occur only rarely in association with its primary infection or reactivation. The mechanism by which EBV produces neurological disease is unknown. This article describes two cases of polymerase-chain-reaction-proven EBV brainstem encephalitis. The sera of both patients contained autoantibodies against N-methyl-D-aspartate receptor (NMDAR), suggesting the presence of a secondary immunological mechanism. Prospective studies are needed to reveal whether the subgroup of patients with EBV encephalitis and anti-NMDAR antibodies have different clinical presentations and would benefit from immunotherapy.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Anti-NMDA Receptor Encephalitis Which Has Shown Clinical Symptoms of Schizophrenia
- Anti-N-methyl-D-aspartate Receptor Encephalitis after Herpes Simplex Virus Infection
- Anti-N-Methyl-D-Aspartate Receptor Encephalitis Presenting Progressive Dyslexia: A Case Report
- Anti-N-methyl-D-aspartate Receptor Encephalitis in Illicit Substance Use
- Anti-N-Methyl-D-Aspartate Receptor Encephalitis with Ovarian Teratoma Improved by Prompt Surgery
