J Korean Neurol Assoc.
2021 Nov;39(4):340-342. 10.17340/jkna.2021.4.12.
Anti-N-Methyl-D-Aspartate Receptor Encephalitis with Ovarian Teratoma Improved by Prompt Surgery
- Affiliations
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- 1Department of Neurology, Kyungpook National University Hospital, Daegu, Korea
- 2Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Korea
- KMID: 2521865
- DOI: http://doi.org/10.17340/jkna.2021.4.12
Abstract
- Anti-N-methyl-D aspartate receptor (NMDAR) encephalitis is often accompanied with ovarian teratomas. It has a variety of clinical manifestations including psychiatric symptoms, seizure, and motor dysfunctions. The diagnosis can be definite when clinical symptoms are present and anti-NMDAR antibodies in cerebrospinal fluid are detected. However, in patients with suspected anti-NMDAR encephalitis with teratomas, early surgery may help the clinical outcome even if the antibodies are initially negative. The authors report a patient whose clinical symptoms improved significantly after early removal of teratoma.
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