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Combination Therapy of the Active KRAS-Targeting Antibody inRas37 and a PI3K Inhibitor in Pancreatic Cancer

Lee JE, Woo MG, Jung KH, Kang YW, Shin SM, Son MK, Fang Z, Yan HH, Park JH, Yoon YC, Kim YS, Hong SS

KRAS activating mutations, which are present in more than 90% of pancreatic cancers, drive tumor dependency on the RAS/ mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K)/AKT signaling pathways. Therefore,...
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CT Findings From Interstitial Lung Diseases in Patients With Metastatic Breast Cancer Treated With FamTrastuzumab Deruxtecan: A Single Institutional Experience

Jang YJ, Jeong JH, Kim JE, Ahn JH, Jung KH, Kim SB

This single-institute, retrospective cohort study enrolled patients with human epidermal growth factor receptor 2-positive metastatic breast cancer treated with trastuzumab deruxtecan between August 2017 and January 2021 from four previous...
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Management of complicated crown fracture by tooth fragment reattachment with fiber post: a case report

Kim YR, Jung KH, Son SA, Park JK

Dental trauma is very common in children and relatively young people, with the line of treatment depending on the time elapsed, age of the child, and tooth maturity. If the...
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Tumor-Infiltrating Lymphocytes in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Receiving Neoadjuvant Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab

Ha JY, Kim JE, Lee HJ, Jeong JH, Ahn JH, Jung KH, Gong G, Chae EY, Kim HH, Chung IY, Ko BS, Kim SB

Purpose: The tumor-infiltrating lymphocytes (TILs) expression in breast cancer is a positive prognostic marker for certain breast cancer subtypes. We evaluated the efficacy of dual antihuman epidermal growth factor receptor...
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Cerebral Venous Sinus Thrombosis Presenting as Ménière’s-Disease-Mimicking Symptoms

Yoon S, Lee HS, Jung M, Lee SA, Jung KH

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Implications of Tamoxifen Resistance in Palbociclib Efficacy for Patients with Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: Subgroup Analyses of KCSG-BR15-10 (YoungPEARL)

Lee J, Im SA, Kim GM, Jung KH, Kang SY, Park IH, Kim JH, Ahn HK, Park YH

Purpose YoungPEARL (KCSG-BR15-10) trial demonstrated a significant progression-free survival (PFS) benefit for premenopausal patients with hormone receptor–positive/human epidermal growth factor receptor 2–negative (HR+/HER2–) metastatic breast cancer (MBC) for palbociclib plus...
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Cerebrovascular Reservoir and Arterial Transit Time Changes Assessed by Acetazolamide-Challenged Multi-Phase Arterial Spin Labeling Perfusion MRI in Chronic Cerebrovascular Steno-Occlusive Disease

Hwang I, Sohn CH, Jung KH, Yeon EK, Lee JY, Yoo RE, Kang KM, Yun TJ, Choi SH, Kim Jh

Purpose: To explore cerebrovascular reservoir (CVR) and arterial transit time (ATT) changes using acetazolamide-challenged multi-phase arterial spin labeling (MP-ASL) perfusion-weighted MRI in chronic cerebrovascular steno-occlusive disease. Materials and Methods: This retrospective...
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Evaluation of sleep quality and stress response in patients requiring dental prosthetic treatment

Jeon HM, Jung KH, Choi NR, Song JM, Lee SH, Kim SY

Purpose: The purpose of this study is to investigate the stress response and sleep state of the new patients who visit the hospital for prosthodontic treatment due to tooth loss...
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Orthodontic intrusion treatment of mandibular anterior teeth in a periodontal patient with hyperdivergent skeletal pattern: 8-year follow-up

Kwon EY, Jung KH, Park SB, Kim Ss, Kim Yi, Choi Yk

Patients who have extruded anterior teeth and deep bite with pathologic tooth migration, it is necessary not only periodontal treat-ment for reduce inflammation, but also orthodontic treatment for intrusion of...
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Treatment of a tooth with furcation involvement and extensive alveolar bone resorption due to endodontic-periodontal combined lesion using root resection: a case report

Choi YK, Kim SY, Jeon HM, Jung KH, Choi NR, Joo JY, Kim HJ, Kwon EY

Due to the complex anatomical structure of the molar, endodontic-periodontal combined lesions often occur, resulting in furcation involvement and extensive alveolar bone resorption. When endodontic-periodontal combined lesions occur through the...
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A humeral hemiarthroplasty with biologic resurfacing of the glenoid using an allo-Achilles tendon: two case reports

Choi KY, Jung KH, Kim YK, Yoon YH

A hemiarthroplasty with biologic resurfacing of the glenoid is one procedure that can be performed in young patients where total shoulder arthroplasty may be difficult. The authors introduced two cases...
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The dual-port endoscope-assisted cyst enucleation on the maxillofacial region

Choi H, Cho GJ, Jung KH, Jeon JY, Lim SW, Park CJ, Hwang KG

Background: Endoscope-assisted surgery is a surgical method that has been used in oral and maxillofacial surgical fields. It provides good illumination, clear, and magnified visualization of the operative field. The...
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Temporary replacement of congenital missing incisors on mandible using temporary anchorage devices in growing patient: 2-year follow-up

Choi Yk, Kwon EY, Jung KH, Choi NR, Park SB, Kim Ss, Kim Yi

Agenesis of permanent tooth in adolescent patients can be treated either by orthodontic treatment for space closure or by main-taining the space until implant restoration can be carried out in...
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A multidisciplinary approach to restore crown-root fractured maxillary central incisors: orthodontic extrusion and surgical extrusion

Kwon EY, Kim SY, Jung KH, Choi YK, Kim HJ, Joo JY

To restore a tooth with a fracture line extending below the marginal bone level, a surgical crown lengthening procedure accompanied by ostectomy could be considered to expose the fracture line...
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Erratum: Correction of Author Name and Affiliation in the Article “Artificial Intelligence in Health Care: Current Applications and Issues”

Park CW, Seo SW, Kang N, Ko B, Choi BW, Park CM, Chang DK, Kim H, Kim H, Lee H, Jang J, Ye JC, Jeon JH, Seo JB, Kim KJ, Jung KH, Kim N, Paek S, Shin SY, Yoo S, Choi YS, Kim Y, Yoon HJ

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The Attitudes of Physicians and the General Public toward Prognostic Disclosure of Different Serious Illnesses: a Korean Nationwide Study

Oh SN, Kim YA, Kim YJ, Shim HJ, Song EK, Kang JH, Kwon JH, Lee JL, Lee SN, Maeng CH, Kang EJ, Do YR, Yun HJ, Jung KH, Yun YH

Background: Although international guidelines recommend palliative care approaches for many serious illnesses, the palliative needs of patients with serious illnesses other than cancer are often unmet, mainly due to insufficient...
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Artificial Intelligence in Health Care: Current Applications and Issues

Park CW, Seo SW, Kang N, Ko BS, Choi BW, Park CM, Chang DK, Kim H, Kim Hc, Lee Hn, Jang Jh, Ye JC, Jeon JH, Seo JB, Kim KJ, Jung KH, Kim N, Paek Sw, Shin SY, Yoo Sy, Choi YS, Kim Y, Yoon HJ

In recent years, artificial intelligence (AI) technologies have greatly advanced and become a reality in many areas of our daily lives. In the health care field, numerous efforts are being...
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Selonsertib Inhibits Liver Fibrosis via Downregulation of ASK1/ MAPK Pathway of Hepatic Stellate Cells

Yoon YC, Fang Z, Lee JE, Park JH, Ryu JK, Jung KH, Hong SS

Liver fibrosis constitutes a significant health problem worldwide due to its rapidly increasing prevalence and the absence of specific and effective treatments. Growing evidence suggests that apoptosis-signal regulating kinase 1...
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Causes, Risk Factors, and Clinical Outcomes of Stroke in Korean Young Adults: Systemic Lupus Erythematosus is Associated with Unfavorable Outcomes

Kwon HS, Kim YS, Lee JM, Koh SH, Kim HY, Kim C, Lee SH, Jung KH, Kim YD, Kwon HM, Kim BJ, Kim JM, Kim BJ, Heo SH, Chang DI, on Behalf of the SKY Investigators

Background and Purpose: The incidence of ischemic stroke (IS) in young adults is increasing, and the associated large socioeconomic impact makes understanding IS in young adults important. We investigated the...
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Incidence and Characteristics of Immediate Substitutions of Injured Players in Korean Professional Football League Matches

Park KB, Jung KH, Kim CR, Hwang IY, Jang SM

Purpose: To identify the incidence and characteristics of immediate substitutions of injured players that occurred during Korean professional football league matches. Methods: This study included injuries that resulted in immediate substitutions...
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