J Cardiovasc Ultrasound.  2014 Mar;22(1):32-35. 10.4250/jcu.2014.22.1.32.

Dilated Cardiomyopathy Secondary to Hypothyroidism: Case Report with a Review of Literatures

• Seol MD
• Lee YS
• Kim DK
• Choi YH
• Kim DJ
• Park SH
• Cho HJ
• Cho WH

• KMID: 2177454
• DOI: http://doi.org/10.4250/jcu.2014.22.1.32

Abstract

To date, it has been well documented that there is a relationship between alterations in thyroid hormones and cardiac dysfunction. We experienced a case of a 36-year-old man with dilated cardiomyopathy (DCM) accompanied by undiagnosed primary hypothyroidism. In the current case, there was a significant improvement in the cardiac function following heart failure management and thyroid hormone replacement. Our case highlights that clinicians should consider the possibility of hypothyroidism as a cause of DCM.

Keyword

Dilated cardiomyopathy; Hypothyroidism

MeSH Terms

Adult
Cardiomyopathy, Dilated*
Heart Failure
Humans
Hypothyroidism*
Thyroid Gland
Thyroid Hormones
Thyroid Hormones

Figure

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  Fig. 1 Initial chest X-ray. A posteroanterior chest X-ray view shows cardiomegaly and both pleural effusions before treatment.

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  Fig. 2 The 12-lead electrocardiography findings. On admission, the patient had normal sinus rhythm with low voltage of limb leads, interventricular conduction delay and nonspecific ST-segment and T-wave changes.

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  Fig. 3 Color Doppler of mitral regurgitation. A: Initial color Doppler findings. B: At a follow-up, there was no mitral regurgitation.

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  Fig. 4 A fine-needle aspiration biopsy findings. A fine-needle aspiration biopsy of the nodule shows adenomatous hyperplasia in a background of lymphocytic thyroiditis (Papanicolaou's stain, × 450).

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  Fig. 5 Follow-up chest X-ray. At a follow-up, a posteroanterior chest X-ray view shows normalized heart size at 16 months after thyroid hormone supplementation and heart failure treatment.

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