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Follow-up of infants with congenital hypothyroidism and low total thyroxine/thyroid stimulating hormone on newborn screen

McCormick , Pitts L, Hughes Z

PURPOSE: Newborn screening (NBS) methods to detect congenital hypothyroidism (CH) vary regarding whether total thyroxine (T4), thyroid stimulating hormone (TSH), or both are measured. Neonates with low T4 and normal...
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Association High-Iodine-Containing Seaweed Soup Consumption after Birth and Subclinical Hypothyroidism in Korean Women: Korea National Health and Nutrition Examination Survey IV (2013–2015)

Kim H, Lee HN, Ha J

BACKGROUND AND OBJECTIVES: This study was to investigate the association between the previous history of seaweed intake after childbirth and subclinical hypothyroidism (SCH) occurrence in Korean women based on the...
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Risk factors for hypothyroidism in euthyroid thyroid nodule patients with lymphocytic thyroiditis on fine needle aspiration cytology

Lee JM, Ha J, Jo K, Lim Y, Kim MH, Jung CK, Jung SL, Kang MI, Cha BY, Lim DJ

BACKGROUND/AIMS: Lymphocytic thyroiditis as cytology diagnosis from fine needle aspiration (FNA) is frequently detected in patients with thyroid nodules. However, the clinical outcome for upcoming hypothyroid events has been rarely...
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Congenital hypothyroidism due to thyroglobulin deficiency: a case report with a novel mutation in TG gene

Heo S, Jang JH, Yu J

Congenital hypothyroidism (CH) is the most common endocrine disorder in neonates and infants with an incidence of one in 2,000 to one in 4,000 newborns. Primary CH can be caused...
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First Korean case of a STAT1 gene mutation: chronic mucocutaneous candidiasis, hypothyroidism, chronic hepatitis and systemic lupus erythematosus

Kim KI, Lee H, Jung SY, Lee DH, Lee J

Chronic mucocutaneous candidiasis (CMC) is characterized by increased susceptibility to chronic and recurrent infections of the skin, mucous membranes, and nails by Candida species. It is a primary immunodeficiency disorder...
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A Case Report of Severe Hypocalcemia and Hypothyroidism after Tyrosine Kinase Inhibitor Treatment

Lee EK, Lee YK, Hwangbo Y, Lee YJ

After introducing tyrosine kinase inhibitors (TKIs) as promising treatments for radioactive iodine refractory advanced thyroid cancer patients, we more often meet patients with TKI-related hormone and electrolyte imbalances in clinics....
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Final height of Korean patients with early treated congenital hypothyroidism

Lee J, Lee J, Lee DH

PURPOSE: Congenital hypothyroidism (CH) is the most common endocrine disorder in children. Thyroid hormone deprivation results not only in mental retardation but also growth retardation. This study investigates the final...
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A Rare Case of Renal Impairment Caused by Primary Hypothyroidism

Choy J, Yaxley J, Yaxley W

An association between hypothyroidism and renal impairment has rarely been reported in the literature. We describe a case of hypothyroidism that was associated with otherwise unexplained acute kidney impairment, which...
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The relationship between subclinical hypothyroidism and serum levels of uric acid and creatinine in children aged 2–14 years

Sayari S, Molaei Z, Torabi Z

PURPOSE: Hypothyroidism is a clinical syndrome that can lead to elevated levels of serum creatinine and uric acid by causing impaired renal function. Although many studies have been carried out...
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Depression in Patients with Subclinical Hypothyroidism: A Systematic Review and Meta-Analysis

Hwang E, Shin S

BACKGROUND: Symptoms of subclinical hypothyroidism include depression, memory loss, myocardial contractility disorder, lipid metabolic disorder, and atherosclerosis. However, the relationship between subclinical hypothyroidism and depression has not been consistent. Therefore,...
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Alteration of Lipid Profiles in Patients with Subclinical Hypothyroidism

Lee JE, Jeong SJ, Lee SJ, Lee YH, Lee Y, Lee SJ, Kim CH

OBJECTIVE: Overt hypothyroidism has been associated with abnormalities of lipid metabolism; however conflicting results regarding the degree of lipid changes in subclinical hypothyroidism (SCH) have been reported. The aim of...
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Parry-Romberg Syndrome Associated with Hypothyroidism

Lee YH, Lee SE, Kim JY, Kim KN, Lee SB

PURPOSE: We report a case of Parry-Romberg syndrome associated with right enophthalmos, hypotropia, up-gaze limitation, en coup the sabre, morphea, and hypothyroidism. CASE SUMMARY: A 41-year-old woman presented with slowly progressive...
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Clinical Features of Patients with Congenital Hypothyroidism Due to Ectopic Thyroid

Kang H, Lee J, Lee DH

OBJECTIVE: This study aimed to describe the clinical features of patients with congenital hypothyroidism due to ectopic thyroid including locations of ectopic thyroid, thyroid function, age of treatment, and starting...
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Predictors of transient congenital hypothyroidism in children with eutopic thyroid gland

Park IS, Yoon JS, So CH, Lee HS, Hwang JS

PURPOSE: Congenital hypothyroidism (CH) is the most common cause of preventable mental retardation. Recently, the detection of CH cases with eutopic thyroid gland has increased due to neonatal screening programs....
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Intellectual development in preschool children with early treated congenital hypothyroidism

Seo MK, Yoon JS, So CH, Lee HS, Hwang JS

PURPOSE: Delayed treatment of congenital hypothyroidism (CH) is a common cause of mental retardation. The aim of the present study was to evaluate intellectual outcomes in preschool children with treated...
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Spontaneous ovarian hyperstimulation syndrome in a young female subject with a lingual thyroid and primary hypothyroidism

Kim SJ, Yoon JH, Kim HK, Kang HC

No abstract available.
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The Effects of Altered Membrane Cholesterol Levels on Sodium Pump Activity in Subclinical Hypothyroidism

Roy S, Dasgupta A

BACKGROUND: Metabolic dysfunctions characteristic of overt hypothyroidism (OH) start at the early stage of subclinical hypothyroidism (SCH). Na⁺/K⁺-ATPase (the sodium pump) is a transmembrane enzyme that plays a vital role...
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A rare association of central hypothyroidism and adrenal insufficiency in a boy with Williams-Beuren syndrome

Dayal D, Giri D, Senniappan S

Primary hypothyroidism related to morphological and volumetric abnormalities of the thyroid gland is one of the commonest of several endocrine dysfunctions in Williams-Beuren syndrome (WBS). We report a 10-month-old boy...
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Unfavorable Course of Subclinical Hypothyroidism in Children with Hashimoto's Thyroiditis Compared to Those with Isolated Non-Autoimmune Hyperthyrotropinemia

Lee YJ, Jung SY, Jung HW, Kim SY, Lee YA, Lee SY, Shin CH, Yang SW

Subclinical hypothyroidism (SCH) is a common problem in pediatric population, and the natural history of SCH varies depending on its etiology. Whether Hashimoto’s thyroiditis (HT) negatively affects the natural course...
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Radionuclide Esophageal Transit Scintigraphy in Primary Hypothyroidism

Khan SH, Madhu VP, Rather TA, Laway BA

  • KMID: 2367455
  • J Neurogastroenterol Motil.
  • 2017 Jan;23(1):49-54.
  • doi: 10.5056/jnm16063
BACKGROUND/AIMS: Esophageal dysmotility is associated with gastrointestinal dysmotility in various systemic and neuroregulatory disorders. Hypothyroidism has been reported to be associated with impaired motor function in esophagus due to accumulation...
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