Gut Liver.  2011 Mar;5(1):61-64.

Clinical Features of Metastatic Tumors of the Pancreas in Korea: A Single-Center Study

• Yoon WJ
• Ryu JK
• Kim YT
• Yoon YB
• Kim SW
• Kim WH

Abstract

BACKGROUND/AIMS
The purpose of this study was to examine the clinical features of metastatic tumors of the pancreas (MTPs) in Korea.
METHODS
A total of 53 cases (31 males) of pathologically proven MTPs were collected. Clinicopathological characteristics and patient outcomes were evaluated.
RESULTS
The median age at the diagnosis of the MTP was 60 years. The median interval between the diagnoses of primary malignancy and MTP was 2.2 years. Primary malignancies were renal cell carcinoma (RCC) (n=14), gastric cancer (n=11), colorectal cancer (n=5), lymphoma (n=4), non-small cell lung cancer (n=3), gastrointestinal stromal tumor (n=2), melanoma (n=2), small cell lung cancer (n=2), gallbladder cancer (n=2), hepatocellular carcinoma (n=1), thymic carcinoid (n=1), liposarcoma (n=1), cholangiocarcinoma (n=1), osteosarcoma (n=1), breast cancer (n=1), duodenal cancer (n=1), and ovarian cancer (n=1). The median survival after the diagnosis of MTP was 23.1 months. Multivariate analysis showed that prolonged survival was associated with RCC as the primary malignancy, the patient being asymptomatic upon the diagnosis of MTP, the absence of extrapancreatic involvement, and surgery included in the treatment.
CONCLUSIONS
MTPs can occur after a prolonged period from the primary diagnosis. RCC as the primary malignancy, the patient being asymptomatic upon the diagnosis of MTP, the absence of extrapancreatic involvement, and surgery included in the treatment are associated with better prognosis.

Keyword

Pancreas; Neoplasms; Neoplasm metastasis; Renal cell carcinoma; Stomach neoplasms

MeSH Terms

Breast Neoplasms
Carcinoid Tumor
Carcinoma, Hepatocellular
Carcinoma, Non-Small-Cell Lung
Carcinoma, Renal Cell
Cholangiocarcinoma
Colorectal Neoplasms
Duodenal Neoplasms
Gallbladder Neoplasms
Gastrointestinal Stromal Tumors
Humans
Liposarcoma
Lymphoma
Melanoma
Multivariate Analysis
Neoplasm Metastasis
Osteosarcoma
Ovarian Neoplasms
Pancreas
Prognosis
Small Cell Lung Carcinoma
Stomach Neoplasms