- Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway
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Masraksa W, Tanasawet , Hutamekalin P, Wongtawatchai T, Sukketsiri W
- KMID: 2471880
- Nutr Res Pract.
- 2020 Apr;14(2):127-133.
- doi: 10.4162/nrp.2020.14.2.127
BACKGROUND/OBJECTIVES: Non-small cell lung cancer is mostly recognized among other types of lung cancer with a poor prognosis by cause of chemotherapeutic resistance and increased metastasis. Luteolin has been found... -
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- Immunotherapy for Non-small Cell Lung Cancer: Current Landscape and Future Perspectives
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Lim SM, Hong MH, Kim HR
- KMID: 2471050
- Immune Netw.
- 2020 Feb;20(1):e10.
- doi: 10.4110/in.2020.20.e10
Immune checkpoint inhibitors (ICIs) have shown remarkable benefit in the treatment of patients with non-small-cell lung cancer (NSCLC) and have emerged as an effective treatment option even in the first-line... -
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- Performances of CYFRA 21-1, Carcinoembryonic Antigen and Their Combination for Lung Cancer Diagnosis
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Kim JJ, Ahn HJ, Park Y
- KMID: 2466768
- Lab Med Online.
- 2020 Jan;10(1):66-74.
- doi: 10.3343/lmo.2020.10.1.66
BACKGROUND: The aim of this study was to compare the efficiency of cytokeratin 19 fragment (CYFRA 21-1) and carcinoembryonic antigen (CEA) for the diagnosis of lung cancer and to establish... -
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- Correlation of PD-L1 Expression Tested by 22C3 and SP263 in Non-Small Cell Lung Cancer and Its Prognostic Effect on EGFR Mutation–Positive Lung Adenocarcinoma
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Kim T, Cha YJ, Chang YS
- KMID: 2466620
- Tuberc Respir Dis.
- 2020 Jan;83(1):51-60.
- doi: 10.4046/trd.2019.0026
BACKGROUND: Programmed death-ligand 1 (PD-L1) expression is tested by immunohistochemistry (IHC)—22C3, SP263, and SP142. The aim of this study is to evaluate the correlation among the three methods of PD-L1... -
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- A Man Presenting with Sudden Weakness and Pain of the Right Hand, by Non-Small Cell Lung Cancer with Brain Metastases
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Sung WJ, Hong BY, Kim JS, Yoo JW, Lim SH
- KMID: 2470353
- Clin Pain.
- 2019 Dec;18(2):88-91.
- doi: 10.35827/cp.2019.18.2.88
Unexplained pain and weakness, i.e., without obvious predisposing factors, are often encountered by physiatrists and efforts should be made to determine the cause. A 63-year-old male presented with radiating pain... -
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- Overcoming the Intrinsic Gefitinib-resistance via Downregulation of AXL in Non-small Cell Lung Cancer
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Jeong I, Song J, Bae SY, Lee SK
- KMID: 2468811
- J Cancer Prev.
- 2019 Dec;24(4):217-223.
- doi: 10.15430/JCP.2019.24.4.217
BACKGROUND: Resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib, is a limited factor in the treatment of non-small-cell lung cancer (NSCLC) patients. Therefore, ongoing studies... -
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- Interobserver Reproducibility of PD-L1 Biomarker in Non-small Cell Lung Cancer: A Multi-Institutional Study by 27 Pathologists
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Chang S, Park HK, Choi YL, Jang SJ, Cardiopulmonary Pathology Study Group of the Korean Society of Pathologists
- KMID: 2465433
- J Pathol Transl Med.
- 2019 Nov;53(6):347-353.
- doi: 10.4132/jptm.2019.09.29
BACKGROUND: Assessment of programmed cell death-ligand 1 (PD-L1) immunohistochemical staining is used for treatment decisions in non-small cell lung cancer (NSCLC) regarding use of PD-L1/programmed cell death protein 1 (PD-1)... -
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- Recent Trends in Demographics, Surgery, and Prognosis of Patients with Surgically Resected Lung Cancer in a Single Institution from Korea
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Yun JK, Lee HP, Lee GD, Kim HR, Kim YH, Kim DK, Park SI, Choi S
- KMID: 2463685
- J Korean Med Sci.
- 2019 Nov;34(45):e291.
- doi: 10.3346/jkms.2019.34.e291
BACKGROUND: Over the past few decades, demographics information has changed significantly in patients with surgically resected lung cancer. Herein, we evaluated the recent trends in demographics, surgery, and prognosis of... -
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- Methionyl-tRNA Synthetase is a Useful Diagnostic Marker for Lymph Node Metastasis in Non-Small Cell Lung Cancer
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Lee JM, Kim T, Kim EY, Kim A, Lee DK, Kwon NH, Kim S, Chang YS
- KMID: 2460216
- Yonsei Med J.
- 2019 Nov;60(11):1005-1012.
- doi: 10.3349/ymj.2019.60.11.1005
PURPOSE: Identification of lymph node (LN) metastasis in non-small cell lung cancer (NSCLC) is critical for disease staging and selection of therapeutic modalities. Sometimes it is not possible to obtain... -
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- Discordance of Epidermal Growth Factor Receptor Mutation between Brain Metastasis and Primary Non-Small Cell Lung Cancer
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Kim KM, Lee SH, Kim SM, Kim NY, Gwak HS, Shin SH, Kwon JW, Yoo H
- KMID: 2461187
- Brain Tumor Res Treat.
- 2019 Oct;7(2):137-140.
- doi: 10.14791/btrt.2019.7.e44
BACKGROUND: The aim of this study was to compare epidermal growth factor receptor (EGFR) mutations between non-small cell lung cancer (NSCLC) and corresponding brain metastases (BMs) in Korea society. METHODS: From... -
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- Demographic and Socioeconomic Factors for Renouncing Further Active Therapy for Patients with Brain Metastasis of Non-Small Cell Lung Cancer
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Jung G, Kim SH, Kim TG, Kim YZ
- KMID: 2461184
- Brain Tumor Res Treat.
- 2019 Oct;7(2):112-121.
- doi: 10.14791/btrt.2019.7.e35
BACKGROUND: As patients with brain metastasis (BM) of non-small cell lung cancer (NSCLC) have dismal prognosis, some of them decide to discontinue further treatment for BM. The objective of this... -
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- Clinical Significance of Pleural Attachment and Indentation of Subsolid Nodule Lung Cancer
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Kim HJ, Cho JY, Lee YJ, Park JS, Cho YJ, Yoon HI, Chung JH, Cho S, Kim K, Lee KW, Lee JH, Lee CT
- KMID: 2460602
- Cancer Res Treat.
- 2019 Oct;51(4):1540-1548.
- doi: 10.4143/crt.2019.057
PURPOSE: Lung cancers presenting as subsolid nodule commonly have peripheral location, making the cancer-pleura relationship noteworthy. We aimed to evaluate the effect of pleural attachment and/or indentation on visceral pleural... -
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- Report of the Korean Association of Lung Cancer Registry (KALC-R), 2014
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Choi CM, Kim HC, Jung CY, Cho DG, Jeon JH, Lee JE, Ahn JS, Kim SJ, Kim Y, Choi YD, Suh YG, Kim JE, Lee B, Won YJ, Kim YC
- KMID: 2460589
- Cancer Res Treat.
- 2019 Oct;51(4):1400-1410.
- doi: 10.4143/crt.2018.704
PURPOSE: The aim of this study was to investigate epidemiology, clinical characteristics and sex differences of patients with lung cancer using nationwide registry in Korea. MATERIALS AND METHODS: The Korean Association... -
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- Chemoradiotherapy versus radiotherapy alone following induction chemotherapy for elderly patients with stage III lung cancer
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Kim DY, Song C, Kim SH, Kim YJ, Lee JS, Kim JS
- KMID: 2460742
- Radiat Oncol J.
- 2019 Sep;37(3):176-184.
- doi: 10.3857/roj.2019.00087
PURPOSE: It is unclear whether adding concurrent chemotherapy (CT) to definitive radiotherapy (RT) following induction CT is a tolerable and cost effective treatment for non-small-cell lung cancer (NSCLC) patients aged... -
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- Prognostic value of neutrophil-to-lymphocyte ratio in locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy
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Park EY, Kim YS, Choi KH, Song JH, Lee HC, Hong SH, Kang JH
- KMID: 2460741
- Radiat Oncol J.
- 2019 Sep;37(3):166-175.
- doi: 10.3857/roj.2019.00220
PURPOSE: This study aimed to investigate neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as prognostic factors in patients with locally advanced non-small cell lung cancer (NSCLC) who received concurrent chemoradiotherapy... -
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- Local ablative radiotherapy for oligometastatic non-small cell lung cancer
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Suh YG, Cho J
- KMID: 2460739
- Radiat Oncol J.
- 2019 Sep;37(3):149-155.
- doi: 10.3857/roj.2019.00514
In metastatic non-small cell lung cancer (NSCLC), the role of radiotherapy (RT) has been limited to palliation to alleviate the symptoms. However, with the development of advanced RT techniques, recent... -
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- Clinical factors affecting progression-free survival with crizotinib in ALK-positive non-small cell lung cancer
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Ock CY, Yoo SH, Keam B, Kim M, Kim TM, Jeon YK, Kim DW, Chung DH, Heo DS
- KMID: 2457035
- Korean J Intern Med.
- 2019 Sep;34(5):1116-1124.
- doi: 10.3904/kjim.2018.011
BACKGROUND/AIMS: Although crizotinib is standard chemotherapy for advanced anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC), clinical factors affecting progression-free survival (PFS) have not been reported. The purpose of... -
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- Preoperative Risk Factors for Pathologic N2 Metastasis in Positron Emission Tomography-Computed Tomography–Diagnosed N0–1 Non-Small Cell Lung Cancer
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Yoon TH, Lee CH, Park KS, Bae CH, Cho JW, Jang JS
- KMID: 2455147
- Korean J Thorac Cardiovasc Surg.
- 2019 Aug;52(4):221-226.
- doi: 10.5090/kjtcs.2019.52.4.221
BACKGROUND: Accurate mediastinal lymph node staging is vital for the optimal therapy and prognostication of patients with lung cancer. This study aimed to determine the preoperative risk factors for pN2... -
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- A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer
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Lim TY, Park S, Kang CH
- KMID: 2455145
- Korean J Thorac Cardiovasc Surg.
- 2019 Aug;52(4):195-204.
- doi: 10.5090/kjtcs.2019.52.4.195
Lobectomy is considered the standard strategy for early-stage non-small cell lung cancer (NSCLC). However, sublobar resection for NSCLC has recently received increased attention. The objective of this study was to... -
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- Association between Expression of 8-OHdG and Cigarette Smoking in Non-small Cell Lung Cancer
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An AR, Kim KM, Park HS, Jang KY, Moon WS, Kang MJ, Lee YC, Kim JH, Chae HJ, Chung MJ
- KMID: 2454601
- J Pathol Transl Med.
- 2019 Jul;53(4):217-224.
- doi: 10.4132/jptm.2019.02.20
BACKGROUND: Exposure to cigarette smoking (CS) is a major risk factor for the development of lung cancer. CS is known to cause oxidative DNA damage and mutation of tumor-related genes,... -
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