Korean J Pediatr.  2005 Feb;48(2):208-211.

A Case of Basaloid Squamous Cell Lung Carcinoma in an 11-year-old Boy

• Kim NC
• Kim SS
• Seo WS
• Park KB
• Park JS
• Shin SM
• Cho HD

Abstract

Primary lung cancer is unusual in children; the squamous cell variant is extremely rare. Lung cancer is classified by histologic types into small-cell lung cancer, non-small cell lung caner, carcinoid, mucoepidermoid carcinoma, and adenoid cystic carcinoma. Furthermore, non-small cell lung cancer is subclassified into adenocarcinoma, large-cell carcinoma, and squamous cell carcinoma. The incidence of lung cancer is influenced by smoking, especially in squamous cell carcinoma, and large cell carcinoma. The present treatments for these tumors are chemotherapy, radiation therapy, and surgical resection depending on their histologic types or stages, but yield very poor survival rates. In this article, we report a case of basaloid squamous cell lung carcinoma in an 11-year-old boy who had symptoms of both leg weakness and back pain radiating to both legs. We confirmed the primary lung carcinoma cells by percutaneous transthoracic needle biopsy. The metastatic carcinoma cells were identified at the bone marrow and lumbar spine. We treated with a combination chemotherapy and radiation therapy. However, he expired 4 months after the onset of disease.

Keyword

Children; Basaloid squamous cell lung carcinoma

MeSH Terms

Adenocarcinoma
Back Pain
Biopsy, Needle
Bone Marrow
Carcinoid Tumor
Carcinoma, Adenoid Cystic
Carcinoma, Large Cell
Carcinoma, Mucoepidermoid
Carcinoma, Non-Small-Cell Lung
Carcinoma, Squamous Cell
Child*
Drug Therapy
Drug Therapy, Combination
Humans
Incidence
Leg
Lung Neoplasms
Lung*
Male*
Smoke
Smoking
Spine
Survival Rate
Smoke