Korean J Med.
2016 May;90(5):449-454. 10.3904/kjm.2016.90.5.449.
Spontaneously Regressed Immunoglobulin IgG4-related Lung Disease Presenting as Multiple Cavitary Nodules
- Affiliations
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- 1Department of Internal Medicine, Veterans Health Service Medical Center, Seoul, Korea. lregulus38@gmail.com
- 2Department of Pathology, Veterans Health Service Medical Center, Seoul, Korea.
- KMID: 2163242
- DOI: http://doi.org/10.3904/kjm.2016.90.5.449
Abstract
- Immunoglobulin (Ig) G4-related disease was recently recognized as a systemic fibro-inflammatory disease characterized by dense lymphoplasmacytic infiltrates, storiform fibrosis, and obliterative phlebitis with IgG4-positive cells in the target tissues. This disease can localize to a single organ or be diffuse in multiple organs. Pulmonary manifestation in IgG4-related lung disease presents as various sized nodules, lung masses, patchy ground-glass opacities, consolidation, thickened bronchovascular bundles, nodular pleural lesions, and interstitial lung disease. Traditional treatment for IgG4-related lung disease includes systemic (cortico) steroids. Here, we report a case of IgG4-related lung disease presenting as multiple cavitary nodules that spontaneously regressed without systemic steroid use.
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