Tuberc Respir Dis.  2000 Jul;49(1):105-110. 10.4046/trd.2000.49.1.105.

A Case of chronic necrotizing pulmonary aspergillosis with pulmonary artery aneurysm

• Kim HJ
• Chung HY
• Kim SH
• Yun JC
• Lee JD
• Hwang YS

• KMID: 2160260
• DOI: http://doi.org/10.4046/trd.2000.49.1.105

Abstract

Pulmonary aspergillosis is classified as a saprophytic, allergic, and invasive disease. Chronic necrotizing pulmonary aspergillosis is categorized as an invasive pulmonary aspergillosis. Most invasive pulmonary aspergillosis have acute and toxic clinical features but chronic necrotizing pulmonary aspergillosis is characterized by a sub-acute infection, most commonly seen in patients with altered local defense system from preexisting pulmonary disease of in mild immunocompromised patients. Pulmonary artery aneurysm due to this infection is termed as a mycotic aneurysm, etiology of which are tuberculosis, syphilis, bacteria and fungus. We report a case chronic necrotizing pulmonary aspergillosis complicating pulmonary aneurysm is a 62 year-old man who was presented with cough, sputum, and fever. Chest radiographs showed a rapid, progressive cavitary lesion and pulmonary artery aneurysm. Angioinvastion of aspergillus was revealed by pathology after operative removal of left upper lobe containing the pulmonary artery aneurysm. He was treated with itraconazole.

Keyword

Invasive pulmonary aspergillosis; Chronic necrotizing pulmonary aspergillosis; Pulmonary artery aneurysm

MeSH Terms

Aneurysm*
Aneurysm, Infected
Aspergillus
Bacteria
Cough
Fever
Fungi
Humans
Immunocompromised Host
Invasive Pulmonary Aspergillosis*
Itraconazole
Lung Diseases
Pathology
Pulmonary Artery*
Pulmonary Aspergillosis
Radiography, Thoracic
Sputum
Syphilis
Tuberculosis
Itraconazole