Tuberc Respir Dis.  2007 Oct;63(4):368-371.

A Case of Chronic Necrotizing Pulmonary Aspergillosis Obscured by Cavitary Pulmonary Tuberculosis

• Min JW
• Yoon YS
• Park JS
• Kim HR
• Rhee JY
• Yoo CG
• Kim YW
• Han SK
• Shim YS
• Yim JJ

Abstract

Pulmonary cavities are caused by bacterial pneumonia, fungal diseases, lung cancer, and tuberculosis (TB). However, in Korea, patients with cavitary lung lesions are generally considered to have pulmonary TB, where the incidence of TB is approximately 70 /100,000 per year. We report a case of chronic necrotizing pulmonary aspergillosis that was obscured by multidrug-resistant pulmonary TB.

Keyword

Tuberculosis; Aspergillosis; Pulmonary cavity

MeSH Terms

Aspergillosis
Humans
Incidence
Invasive Pulmonary Aspergillosis*
Korea
Lung
Lung Diseases
Pneumonia, Bacterial
Tuberculosis
Tuberculosis, Pulmonary*

Figure

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  Figure 1 Initial CT shows cavitary lesion with air space consolidation, left. Follow-up CT after 2 months of anti-tuberculosis medication revealed aggravated lesion, right.

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  Figure 2 Resected lung tissue shows 5 cm sized cavity filled with necrotic materials accompanied with dense peripheral fibrosis.

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  Figure 3 Microscopic view of resected lung tissue. Fungal hyphae are seen in the left upper area, H&E stain(×200), left. GMS stain (×400), right.

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