Ann Dermatol.  2007 Dec;19(4):173-175. 10.5021/ad.2007.19.4.173.

Gefitinib-induced Paronychia Teated by Cyosurgery

Affiliations
  • 1Department of Dermatology, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Korea. jmyang@smc.samsung.co.kr
  • 2Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, Korea.

Abstract

Gefitinib (Iressa, ZD1839) is one of the epidermal growth factor receptor (EGFR) inhibitors approved for the treatment of advanced non-small cell lung cancer. The cutaneous reactions to EGFR inhibitors manifest as a follicular eruption, nail toxicity, xerosis, or desquamation. These adverse events, if not properly managed, can interfere with activities of daily living. We report a case of paronychia induced by gefitinib successfully treated with cryosurgery which is a simple and safe treatment.

Keyword

Cryosurgery; Gefitinib; Paronychia

MeSH Terms

Activities of Daily Living
Carcinoma, Non-Small-Cell Lung
Cryosurgery
Paronychia*
Receptor, Epidermal Growth Factor
Receptor, Epidermal Growth Factor
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