Korean J Crit Care Med.  2015 Nov;30(4):258-264. 10.4266/kjccm.2015.30.4.258.

The Prognostic Factors of Pneumonia with Septic Shock in Patients Presenting to the Emergency Department

Affiliations
  • 1Department of Emergency Medicine, Gachon University, Gil Medical Center, Incheon, Korea. empearl@gilhospital.com
  • 2Department of Family Medicine, Gachon University, Gil Medical Center, Incheon, Korea.
  • 3Department of Neurology, Gachon University, Gil Medical Center, Incheon, Korea.

Abstract

BACKGROUND
Pneumonia is the most common cause of death among patients with infectious disease in Korea. However, studies of pneumonia with septic shock in patients presenting to the emergency department are limited. The aim of this study was to investigate the prognostic factors associated with pneumonia with septic shock in patients presenting to the emergency department.
METHODS
From January 2008 to September 2014, patients with pneumonia with septic shock admitted through the emergency department were retrospectively examined.
RESULTS
Of the 561,845 patients who visited the emergency department, 398 were admitted for pneumonia with septic shock. The 28-day mortality rate in these patients was 36.4%. The independent prognostic factors were old age (>70 yrs) (odds ratio [OR], 2.42; 95%, confidence interval [CI], 1.35-4.32), Acute Physiology and Chronic Health Evaluation (APACHE) II score (OR, 1.04; 95% CI, 1.01-1.08), leukopenia (OR, 3.63; 95% CI, 1.48-8.94), prolonged PT-INR (OR, 2.53; 95% CI, 1.41-4.54), and hypoxemia (OR, 2.88; 95% CI, 1.30-6.38).
CONCLUSIONS
A poor prognosis of patients with pneumonia is associated with old age (>70 yrs), increased APACHE II score, leukopenia, prolonged PT-INR, and hypoxemia.

Keyword

mortality; outcome; pneumonia; shock, septic

MeSH Terms

Anoxia
APACHE
Cause of Death
Communicable Diseases
Emergencies*
Emergency Service, Hospital*
Humans
Korea
Leukopenia
Mortality
Pneumonia*
Prognosis
Retrospective Studies
Shock, Septic*

Figure

  • Fig. 1. Flow diagram of patients in this study. ED: emergency department.


Reference

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