Korean J Neurotrauma.  2013 Oct;9(2):139-141. 10.13004/kjnt.2013.9.2.139.

Superficial Siderosis in Central Nervous System: A Case Report and Literature Review

• Lee GY
• Park HS
• Shim YS
• Hyun DK
• Kim EY
• Yoon SH
• Park HC
• Park CO

• KMID: 2156116
• DOI: http://doi.org/10.13004/kjnt.2013.9.2.139

Abstract

Superficial siderosis (SS) in central nervous system is a rare, slowly progressive disease and usually misdiagnosed or diagnosed too late when the patient is chronically devastated. A 55-year-old man with deafness and gait disturbance for ten years was referred from otorhinologist for evaluation of brain. Magnetic resonance image (MRI) showed symmetric hypointense rim partially delineated the bilateral hemisphere on gradient-recalled-echo T2-weighted image, and it was diagnosed as hemosiderin deposition in subarachnoid and subpial meningeal layer. The correct diagnosis of cerebral superficial siderosis can be achieved by careful neurological examination and MRI because computed tomography findings and symptoms are ambiguous. Serial follow-up of imaging study and education for patient are necessary to prevent progression of SS.

Keyword

Superficial siderosis; Sensorineural hearing loss; Hemosiderin; MRI

MeSH Terms

Brain
Central Nervous System*
Deafness
Diagnosis
Education
Follow-Up Studies
Gait
Hearing Loss, Sensorineural
Hemosiderin
Humans
Magnetic Resonance Imaging
Middle Aged
Neurologic Examination
Siderosis*
Hemosiderin

Figure

• 

  FIGURE 1. A, B: Axial and Coronal T2-weighted MR images show a variably thick hypointense rim outlined the brain stem and various cisterns. C, D: Axial gradient-recalled-echo T2-weighted images show a symmetric well-defined hypointense rim that delineated the cerebellum, some of the lower cranial nerves, bilateral sylvian fissures and other leptomeningeal layers.

Reference

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