J Korean Soc Pediatr Nephrol.  2001 Oct;5(2):188-195.

A Case of Membranoproliferative Glomerulonephritis Type II: Dense Deposit Disease, DDD

• Kwon HS
• Oh SJ
• Lee YM
• Kim JH
• Kim PK
• Kang HY
• Jeong HJ
• Choi IJ

Abstract

Type II membranoproliferative glomerulonephritis (Dense deposit disease ) is an acquired primary glomerular disease characterized by electron microscopic evidence of a continuous dense membrane deposition replacing the lamina densa. It is a subtype of idiopathic membra- noproliferative glomrulonephritis, and was described as a separate entity by Berger and Galle in 1963. It frequently occurs in older chilren and young adults and the clinical course is variable, but is generally progressive. The presenting feature is nephrotic syndrome in many patients, and proteinuria and hematuria are also seen frequently. The purpose of this paper is to present a case of DDD (Dense deposit disease) from a 10 year old boy who was diagnosed as a acute poststreptococcal glomurulonephritis with protenuria, hematuria, and facial edema by renal biopsy 4 years ago.

Keyword

Acquired primary glomerular disease; Dense deposit disease; Memmbranoproliferative glomerulonephritis; Proteinuria; Hematuria; Acute poststreptococcal glomerulonephritis

MeSH Terms

Biopsy
Child
Dichlorodiphenyldichloroethane*
Edema
Glomerulonephritis, Membranoproliferative*
Hematuria
Humans
Male
Membranes
Nephrotic Syndrome
Proteinuria
Young Adult
Dichlorodiphenyldichloroethane