Korean J Hematol.
1997 Aug;32(2):318-323.
A Case of Recurrent Subacute Necrotizing Lymphadenitis with Pancytopenia
- Affiliations
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- 1Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
- 2Institute for Clinical Molecular Biology Research, Soonchunhyang University College of Medicine, Seoul, Korea.
Abstract
- We report a case of recurrent subacute necrotizing lymphadenitis with pancytopenia in 21-years-old-woman. She was admitted to our hospital 4-years interval with fever and abdominal pain. Laboratory findings of the last admission showed pancytopenia, such as WBC 700/microliter, hemoglobin 6.0mmol/L (9.7g/dL), hematocrit 28.8%, and platelet 54,000/microliter. Abdominal CT showed hepatosplenomegaly, enlarged conglomerated lymph nodes in splenic hilum, lesser sac, celiac root, and paraaortic areas. Bone marrow biopsy showed hypocellular marrow (20%) with increased number of megakaryocyte, myeloid hyperplasia, and hemophagocytic histiocytes suggesting infectious process. We performed exploratory laparotomy, and pathologic finding revealed subacute necrotizing lymphadenitis-Kikuchi disease-. She was recovered on 26th hospital day with conservative treatment.
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