Korean J Pediatr Gastroenterol Nutr.  2000 Sep;3(2):212-216. 10.5223/kjpgn.2000.3.2.212.

A Case of Subacute Necrotizing Lymphadenitis with Hepatic Complication in an 11-year-old Boy

Affiliations
  • 1Department of Pediatrics, Red Cross Hospital, Seoul, Korea.
  • 2Department of Pathology, Red Cross Hospital, Seoul, Korea.

Abstract

Subacute necrotizing lymphadenitis was first reported by Kikuchi and Fujimoto in 1972. Young females no more than 30 years of age are mainly affected. It usually manifests as fever and cervical lymphadenopathy. We experienced one case of subacute necrotizing lymphadenitis with hepatic complication in an 11-year-old boy. Symptoms presented were URI signs, diarrhea, headache, and weight loss along with fever and cervical lymphadenopathy. Elevated serum AST/ALT levels were also noted up to 682/1560 (IU/L) and were normalized within one month. We performed aspiration biopsy of the liver twice (at admission and 5 months thereafter). The hepatic histopathologic findings were nonspecific.

Keyword

Hepatitis; Subacute necrotizing lymphadenitis; Kikuchi's disease; Chi

MeSH Terms

Biopsy, Needle
Child*
Diarrhea
Female
Fever
Headache
Hepatitis
Histiocytic Necrotizing Lymphadenitis
Humans
Liver
Lymphadenitis*
Lymphatic Diseases
Male*
Weight Loss
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