Korean J Med.  2007 Sep;73(3):317-323.

Three cases of premature coronary artery disease in systemic lupus erythematosus

• Sohn W
• Lee HH
• Baek YH
• Kwon OW
• Kim SH
• Shin JH
• Bae SC

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disorder with a potential for multisystem organ dysfunction. Systemic lupus erythematosus patients have more frequent and earlier manifested atherosclerosis including coronary artery disease than the general population. We report three patients having SLE that have experienced acute coronary syndrome with onset at a relatively young age. The patients have premature atherosclerosis in a coronary artery as determined by coronary angiography and intravascular ultrasonography (IVUS). We suggest that systemic lupus erythematosus is a significant risk factor for coronary atherosclerosis.

Keyword

Systemic lupus erythematosus; Coronary artery disease; Prematrure; Atherosclerosis; Intravascular ultrasonography

MeSH Terms

Acute Coronary Syndrome
Atherosclerosis
Coronary Angiography
Coronary Artery Disease*
Coronary Vessels*
Humans
Lupus Erythematosus, Systemic*
Risk Factors
Ultrasonography, Interventional