J Korean Pediatr Soc.
1980 Oct;23(10):833-842.
Histiocytic Medullary Reticulosis in childhood Report of Three Cases
- Affiliations
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- 1Deptartment of Pediatirics and Yonsei University, Seoul, Korea.
- 2Department of pathology, College of Medicine, Yonsei Universty, Seoul, Korea.
Abstract
- Three cases of hisiocytic medullary reticulosis occurring in children aged 6 years, 9 years and 14 years, are described. In all children the diagnosis was based on anemia, granulocytopenia, thrombocytopenia and marked erythrophagocytosis by bone marrow and lymph node atypical histiocytes. They all showed immediate remission with combined chemotherapy of vinblastine and prednisolone, but Case 1 eventually died at 6 months after onset of this rapidly progressive, fatal illness and Case 2, 3 are alive 14 months after onset of their illness.
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