J Korean Radiol Soc.  1981 Jun;17(1):89-93. 10.3348/jkrs.1981.17.1.89.

Roentgenological findings of histiocytic medullary reticulosis in the lung

• Kim SY
• Lim JH
• Suh SJ

• KMID: 2463423
• DOI: http://doi.org/10.3348/jkrs.1981.17.1.89

Abstract

Histocytic medullary reticulosis, known as malignant histiocytosis, is a disorder characterized by a systemicproliferation of morphologically abnormal histiocytes with prominent erythrophagocytosis. Fever, wasting, lymphdenopathy, hepatosplenomegaly and pancytopenia are the main clinical pictures. Prognosis is very poor andinvariably die within several months. Authors present radiological findings of pulmonary involvement in 5 cases of histologically proven histiocytic medullary reticulosis. The findings are progressive interstitial, alveolar ormixed infiltrations, small amount of pleural effusion, hilar and/or mediastineal lymph node enlargement and cardiomegaly. Histiocytic medullary reticulosis should be borne in mind in differential diagnosis of any patientswho has unexplanable above radiological findings.

MeSH Terms

Cardiomegaly
Diagnosis, Differential
Fever
Histiocytes
Histiocytic Sarcoma
Lung*
Lymph Nodes
Pancytopenia
Pleural Effusion
Prognosis