Korean J Med.  1998 Jan;54(1):135-139.

A Case of Wernicke Disease in a Patient with Acute Promyelocytic Leukemia

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Wernicke's disease is a condition produced by thiamine deficiency; more than 90% of the cases are observed in chronic alcoholics. Other less frequent conditions associated with Wernicke disease are gastric disorders, prolonged parenteral nutrition, uremia, hemodialysis, hyperemesis gravidarum, prolonged starvation, and AIDS. We report a 41-year-old female patient of Wernicke disease associated with nausea and prolonged parenteral nutrition after chemotherapy of acute promyelocytic leukemia. She has got thiamine replacement therapy and most symptoms were improved. She was discharged after complete remission of leukemia and recovery of normal diet.

Keyword

Wernicke disease; Acute promyelocytic leukemia

MeSH Terms

Adult
Alcoholics
Diet
Drug Therapy
Female
Humans
Hyperemesis Gravidarum
Leukemia
Leukemia, Promyelocytic, Acute*
Nausea
Parenteral Nutrition
Pregnancy
Renal Dialysis
Starvation
Thiamine
Thiamine Deficiency
Uremia
Wernicke Encephalopathy*
Thiamine
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