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A Pilot Study of Trans-Arterial Injection of 166Holmium-Chitosan Complex for Treatment of Small Hepatocellular Carcinoma

Cho BC, Kim EH, Choi HJ, Kim JH, Roh JK, Chung HC, Ahn JB, Lee JD, Lee JT, Yoo NC, Sohn JH

  • KMID: 2428296
  • Yonsei Med J.
  • 2005 Dec;46(6):799-805.
Percutaneous approaches, such as percutaneous ethanol injection and radiofrequency ablation, have been most widely used for hepatocellular carcinoma patients who were not eligible for surgery. New technologies to improve the...
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Efficacy of Postoperative Concurrent Chemoradiation for Resectable Rectal Cancer: A Single Institute Experience

Ahn JB, Chung HC, Yoo NC, Roh JK, Kim NK, Suh CO, Kim GE, Seong JS, Shim WH, Chung HC

  • KMID: 2166136
  • Cancer Res Treat.
  • 2004 Aug;36(4):228-234.
PURPOSE: For patients with Dukes' stage B and C rectal cancer, surgery followed by adjuvant chemoradiotherapy is considered to be the standard treatment. However, the drugs used in combination with...
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Malignant Fibrous Histiocytoma with Type I Neurofibromatosis

Park SH, Lee KY, Kim NK, Sohn SK, Yoo NC, Shim HS, Kim SH, Kim TS, Cho CH

  • KMID: 2096198
  • J Korean Surg Soc.
  • 2004 Aug;67(2):167-170.
Type I neurofibromatosis is an autosomal dominant disorder that occurs in 1 of 3, 000 births. It is characterized by multiple cutaneous neurofibromas, cafe-au-lait spots of the skin. Patients with...
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Phase II Study of Gemcitabine and Vinorelbine as Second-Line Chemotherapy in Non-Small Cell Lung Cancer

Kim YJ, Sohn JH, Kim C, Kim YT, Kim HJ, Ahn JB, Kim SK, Chang J, Yoo NC, Kim JH, Cho JY

  • KMID: 1972896
  • Cancer Res Treat.
  • 2003 Aug;35(4):294-298.
PURPOSE: With the increased use of chemotherapy for non small cell lung cancer (NSCLC), a growing group of patients can now be considered for second-line chemotherapy. However, guidelines for the...
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Paclitaxel and Cisplatin Combination Chemotherapy in Pretreated Breast Cancer

Sohn JH, Kim YT, Rha SY, Yoo NC, Roh JK, Kim BS, Suh CO, Kim GE, Jang WI, Chung HC

  • KMID: 2166187
  • Cancer Res Treat.
  • 2003 Jun;35(3):267-273.
PURPOSE: A single institute trial of combination chemotherapy, with paclitaxel and cisplatin, in patients with metastatic breast cancer, having failed previous combination chemotherapy, was performed. MATERIALS AND METHODS: Patients were...
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Changes of Telomerase Activity and Proliferation by Inhibition of Reverse Transcriptase Activity in Human Cancer Cell

Ji HJ, Park KH, Kim TS, Rha SY, Yoo NC, Kim JM, Kim JS, Roh JK, Jang WI, Chung HC

  • KMID: 2134358
  • Cancer Res Treat.
  • 2002 Jun;34(3):223-233.
PURPOSE: Activation of telomerase is proposed to be an essential step in cancer cell immortalization and cancer progression. 3'-azido-2',3'-dideoxythymidine (AZT), a reverse transcriptase inhibitor, was reported to be incorporated in...
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A case of double primary cancer of hepatocellular carcinoma and mucoepidermoid carcinoma in the liver

Park JY, Kim YM, Kang EW, Kim YS, Shim KY, Yoo NC, Kang H, Park YN, Park C, Roh JK

  • KMID: 1601334
  • Korean J Med.
  • 2001 Aug;61(2):162-167.
Mucoepidermoid carcinoma is a common malignant tumor of the salivary glands, but rare in other sites. Only 10 cases of mucoepidermoid carcinoma of liver have been reported, and there was...
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Experimental and Clinical Studies on the Intraarterial Injection of Holmium-166 Chitosan Complex in the Treatment of Hepatocellular Carcinoma

Lee JT, Kim EK, Won JY, Lee DY, Lee JD, Yoo NC, Park KB, Yoo HS

PURPOSE: The purposes of this study were to evaluate the biodistribution and effect of Ho-166 radionuclide by intra-arterial injection of the Ho-166 chitosan complex in dogs and to assess the...
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Leptomeningeal Carcinomatosis in Solid Tumors; Clinical Manifestation and Treatment

Park JO, Shin HJ, Kim HJ, Lee SW, Jeung HC, Kim SM, Yoo NC, Chung HC, Kim JH, Kim BS, Min JS, Roh JK

  • KMID: 2007124
  • J Korean Cancer Assoc.
  • 2001 Feb;33(1):34-40.
PURPOSE: Leptomeningeal carcinomatosis occurs in about 5% of patients with solid tumor and is being diagnosed with increasing frequency as patients live longer and as neuro-imaging studies improve. In general,...
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Differential Diagnosis By Analysis of Pleural Effusion

Ko WK, Lee JG, Jung JH, Park MS, Jeong NY, Kim YS, Yang DG, Yoo NC, Ahn CM, Kim SK

BACKGROUND: Pleural effusion is one of most common clinical mainifestations associated with a variety of pulmonary disease such as malignancy, tuberculosis, and pneumonia. However, there are no useful laboratory tests...
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Squamous Cell Carcinoma of the Cornea

Shin HJ, Sohn JH, Goo YS, Park JY, Choi CH, Kim EK, Cho SH, Yoo NC, Roh JK

In this paper, a case of corneal squamous cell carcinoma is reported. Invasive squamous cell carcinoma of the cornea is a rare disorder and has not been previously described in...
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Effect of 5 - FU plus leucovorin for adjuvant chemotherapy according to dose related factors in colon cancer

Shim KY, Ahn JB, Jung HC, Park JO, Yoo NC, Rha SY, Roh JK, Kim BS, Kim NK, Min JS, Chung HC

  • KMID: 2080775
  • Korean J Med.
  • 2000 Sep;59(3):290-299.
BACKGROUND: In patients with stage C colon cancer, surgery followed by adjuvant chemotherapy with 5-fluorouracil (5-FU)/leucovorin (LV) is considered to be the standard treatment. However, the objects of...
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The Efficacy and Safety of Docetaxel in Patients with Anthracychne pretreated Metastatic Breast Cancer: A Multicenter Phase II Study

Ahn JB, Shim KY, Park JO, Jung HC, Yoo NC, Chung HC, Kim JH, Choi JH, Kim HS, Kim HC, Kim WK, Roh JK

  • KMID: 2175093
  • J Korean Cancer Assoc.
  • 2000 Apr;32(2):235-243.
PURPOSE: Tbis phase II study was performed to evaluate the efficacy and safety of docetaxel in patients with anthracycline-pretreated metastatic breast cancer (MBC). MATERIALS AND METHODS: From September 1996 to January 1998,...
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Tumor - specific Virus Replication and Cytotoxicity of E1B 55 kD - deleted Adenovirus

Kim J, Lee B, Kim J, Ahn JB, Park JO, Yoo NC, Kim JH, Roh JK, Min JS, Kim BS, Lee H

  • KMID: 2137127
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):200-209.
PURPOSE: To overcome the limitations of cancer gene therapy using replication-incom- petent adenovirus, we generated E1B 55 kD-deleted adenovirus (YKL-1) by polymerase chain reaction (PCR) and homologous recombination. We then investigated tumor-specific virus replication...
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Clinical Significance of Urokinase - type Plasminogen Activator Receptor ( uPAR ) Expression in Breast Cancer Tissues

Gong SJ, Rha SY, Jung HC, Park JO, Yoo NC, Roh JK, Yang WI, Lee KS, Min JS, Kim BS, Chung HC

  • KMID: 2137111
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):53-59.
PURPOSE: Cancer invasion is induced by several proteolytic enzyme systems associated with the destruction of basement membrane and extracellular matrix. Urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor-1 (PAI-1) have been reported as...
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Application of Gabexate Mesylate IC against MMP - 9 Using ex vivo Model in Gastric Cancer: Prognostic Factor and Selection Criteria for Anti - MMP Treatment

Moon YW, Yang H, Jung HC, Rha SY, Kim TS, Yoo NC, Noh SH, Roh JK, Min JS, Kim BS, Chung HC

  • KMID: 2137106
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):7-18.
PURPOSE: Among the many biological characteristics of cancer, matrix metalloproteinases(MMPs) are essential for tumor invasion and metastasis. The correction of the imbalance between MMPs and tissue inhibitors of matrix metalloproteinase...
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Restoration of P-glycoprotein function is involved in the increase of natural killer activity with exogenous interleukin-15 in human immunodeficiency virus-infected individuals

Chang KH, Kim JM, Yoo NC, Kim WH, Park JH, Choi IH, Kim HS, Lee KW, Song YG, Hong SK, Kim HY

A depressed level of natural killer (NK) activity is one of the various immunologic abnormalities in human immunodeficiency virus (HIV) infection. Interleukin-15 (IL-15), an immunotherapeutic candidate in HIV infection, increases...
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Efficacy of Gemcitabine Chemotherpy in Advanced Non-small cell Lung Cancer ( NSCLC ): A Phase 2 Study

Chang HJ, Ahn JB, Lee JG, Shim KY, Rha SY, Kim SK, Chang J, Kim SK, Lee WY, Yoo NC, Chung HC, Roh JK, Kim BS, Choi SJ, Kim TW, Suh CW, Kim JH

  • KMID: 2175190
  • J Korean Cancer Assoc.
  • 1999 Jun;31(3):523-532.
PURPOSE: To evaluate the efficacy and safety of gemcitabine, a pyrimidine antimetabolite against advanced non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Forty patients with unresectable stage IIIb to IV, pathologacally...
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Clinical Relevance of Urokinase-type Plasminogen Activator ( uPA ) , uPA Receptor , Plasminogen Activator Inhibitor-1 Co-expression from Tissue and Serum of Breast Cancer as Targets of Biotherapy

Rha SY, Park JO, Gong SJ, Park SH, Yoo NC, Yang WI, Roh JK, Min JS, Lee KS, Kim BS, Chung HC

  • KMID: 2175221
  • J Korean Cancer Assoc.
  • 1999 Apr;31(2):256-266.
PURPOSE: We measured and compared the uPA, plasminogen activator inhibitor-1 (PAI-1) and uPA receptor (uPAR) levels in breast cancer tissues and blood of the patients to evaluate their clinical relevance...
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The Efficacy of Pre - operative Chamotherapy with Intra-arterial Cisplatin and Intravenous Adriamycin for High Grade Osteosarcoma

Rha SY, Gong SJ, Chung HC, Shim KY, Ahn JB, Yoo NC, Chung HC, Kim JH, Roh HK, Min JS, Kim BS, Shin KH, Yang WI, Lee CI

  • KMID: 2175282
  • J Korean Cancer Assoc.
  • 1999 Feb;31(1):134-143.
PURPOSE: Osteosarcoma is one of the most common juvenile malignant tumors in Korea. Combined modality treatment [pre-operative chemotherapy + surgery (limb salvage or amputation) + adjuvant chemotherapy] had improved...
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