J Korean Pediatr Soc.  1982 Apr;25(4):399-403.

A Case of Disseminated Cryptococcosis with Skin Lesion and Miliary Shadows of the Lung

• Bang CH
• Chi SK
• Kim IH
• Kim SW
• Ko IH

Abstract

A Case of disseminated cryptococcosis in a 5-year old girl is reported. Although twenty four pediatric cases of cryptococcosis were reported in Korea for the past 15years, this case's clinical picture is interesting and make diagnostic difficulties from miliary tuberculosis. She was transferred from a local clinic under the impression of miliary tuberculosis with chest X-ray showing miliary shadows. Mantoux test showed strong positive. She was not vaccinated BCG and had a history of contact with tuberculous patient for a month. Cough, fever and abdominal pain were persisted in spite of antituberculous medications(INH & RMP). CSF examination revealed cryptococcus cyst. Facial skin lesions which looked like Moluscum contagiosum at first became to be umbilicated and disseminated. It was diagtococcal lesions with little inflammatory response. In spite of treatment with 5-FC and Amphotericin B, her general condition became worse and died of respiratory failure. A brief review of the literature was done.

Keyword

Cryptococcosis; dissminated; Millary tuberculosis

MeSH Terms

Abdominal Pain
Amphotericin B
Child, Preschool
Cough
Cryptococcosis*
Cryptococcus
Female
Fever
Humans
Korea
Lung*
Mycobacterium bovis
Respiratory Insufficiency
Skin*
Thorax
Tuberculosis, Miliary
Amphotericin B