J Korean Rheum Assoc.  2010 Jun;17(2):194-199. 10.4078/jkra.2010.17.2.194.

A Case of Disseminated Crytococcosis in a Patient with Systemic Lupus Erythematosus

Affiliations
  • 1Department of Internal Medicine, School of Medicine, Catholic University of Daegu, Daegu, Korea. heeya0035@cu.ac.kr
  • 2Arthritis and Autoimmunity Research Center, Catholic University of Daegu, Daegu, Korea.

Abstract

Disseminated cryptococcosis mainly occurs in immunocompromised patients. It enters the body through the respiratory tract and spreads to the lungs, skin, liver and lymphoid organs. Among cryptococcosis, cryptococcal meningitis is a relatively frequent manifestation and causes serious morbidity and mortality. It needs urgent diagnosis and initiation of effective antifungal therapy. It is difficult to differentiate cryptococcal meningitis from neuropsychiatric lupus due to similar clinical symptoms, laboratory and cerebrospinal fluid findings. We report a case of disseminated cyrptococcosis in a patient with systemic lupus erythematosus being managed with mycophenolate mofetil, prednisolone and hydroxychloroquine.

Keyword

Disseminated cryptococcosis; Systemic lupus erythematosus

MeSH Terms

Cryptococcosis
Humans
Hydroxychloroquine
Immunocompromised Host
Liver
Lung
Lupus Erythematosus, Systemic
Meningitis, Cryptococcal
Mycophenolic Acid
Prednisolone
Respiratory System
Skin
Hydroxychloroquine
Mycophenolic Acid
Prednisolone
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