Korean J Anesthesiol.  2014 Feb;66(2):131-135. 10.4097/kjae.2014.66.2.131.

Comparison of respiratory mechanics between sevoflurane and propofol-remifentanil anesthesia for laparoscopic colectomy

• Bang SR
• Lee SE
• Ahn HJ
• Kim JA
• Shin BS
• Roe HJ
• Sim WS

• KMID: 2092433
• DOI: http://doi.org/10.4097/kjae.2014.66.2.131

Abstract

BACKGROUND
The creation of pneumoperitoneum and Trendelenburg positioning during laparoscopic surgery are associated with respiratory changes. We aimed to compare respiratory mechanics while using intravenous propofol and remifentanil vs. sevoflurane during laparoscopic colectomy.
METHODS
Sixty patients undergoing laparoscopic colectomy were randomly allocated to one of the two groups: group PR (propofol-remifentanil group; n = 30), and group S (sevoflurane group; n = 30). Peak inspiratory pressure (PIP), dynamic lung compliance (Cdyn), and respiratory resistance (Rrs) values at five different time points: 5 minutes after induction of anesthesia (supine position, T1), 3 minutes after pneumoperitoneum (lithotomy position, T2), 3 minutes after pneumoperitoneum while in the lithotomy-Trendelenburg position (T3), 30 minutes after pneumoperitoneum (T4), and 3 minutes after deflation of pneumoperitoneum (T5).
RESULTS
In both groups, there were significant increases in PIP and Rrs while Cdyn decreased at times T2, T3, and T4 compared to T1 (P < 0.001). The Rrs of group PR for T2, T3, and T4 were significantly higher than those measured in group S for the corresponding time points (P < 0.05).
CONCLUSIONS
Respiratory mechanics can be adversely affected during laparoscopic colectomy. Respiratory resistance was significantly higher during propofol-remifentanil anesthesia than sevoflurane anesthesia.

Keyword

Laparoscopy; Propofol; Remifentanil; Respiratory mechanics; Sevoflurane

MeSH Terms

Anesthesia*
Colectomy*
Humans
Laparoscopy
Lung Compliance
Pneumoperitoneum
Propofol
Respiratory Mechanics*
Propofol