Korean J Anesthesiol.  2005 Jan;48(1):95-98. 10.4097/kjae.2005.48.1.95.

Anaphylaxis after Thiopental and Rocuronium Induction: A case report

• Hwang SM
• Suh JW
• Lim SY

• KMID: 2091962
• DOI: http://doi.org/10.4097/kjae.2005.48.1.95

Abstract

Anaphylaxis and anaphylactoid reactions that occur during anesthesia may range from minor systemic effects to life-threatening or fatal effects. A 88-yr-old man was scheduled for laparoscopic nephrectomy. He had no history of allergy and had never previously undergone general anesthesia, though several spinal anesthesias were performed for TUR-B using 0.5% heavy bupivacaine. General anesthesia was induced with alfentanil 0.5 mg, thiopental 250 mg, and rocuronium bromide 50 mg. After thiopental injection, the man became irritable, and after rocuronium injection ventilation became difficult and tachycardia appeared; blood pressure could not be checked. The operation was canceled and a skin prick test was performed. Seven weeks later, he underwent uneventful anesthesia with etomidate and vecuronium.

Keyword

anaphylaxis; anesthesia; rocuronium; thiopental

MeSH Terms

Alfentanil
Anaphylaxis*
Anesthesia
Anesthesia, General
Anesthesia, Spinal
Blood Pressure
Bupivacaine
Etomidate
Hypersensitivity
Nephrectomy
Skin
Tachycardia
Thiopental*
Vecuronium Bromide
Ventilation
Alfentanil
Bupivacaine
Etomidate
Thiopental
Vecuronium Bromide