Korean J Anesthesiol.  2002 May;42(5):641-645. 10.4097/kjae.2002.42.5.641.

Small Dose Intrathecal Morphine for Post-cesarean Analgesia

• Kim AR
• Kim MH

• KMID: 2091690
• DOI: http://doi.org/10.4097/kjae.2002.42.5.641

Abstract

BACKGROUND: The aim of this study is to compare duration of analgesia and incidence of adverse effects between two doses of intrathecal morphine in patients after elective ceasrean section.
METHODS
Group 1 (n = 31) received morphine 0.1 mg and group 2 (n = 28) received morphine 0.2 mg in addition to intrathecal dose of 2.0 ml of 0.5% bupivacaine in 8% dextrose and fentanyl 15ng.
RESULTS
In both groups 1 and 2, excellent postoperative analgesia with long duration was obtained (19.4 +/- 10.1 and 20.5 +/- 11.3 hours, respectively). Fourteen patients (45.2%) in group 1 and 12 patients (42.9%) in group 2 developed mild pruritus that did not require treatment except one patient in group 2 who received nalbuphine 5 mg iv. Incidences of postopertaive nausea or vomiting were not significantly different between the two groups.
CONCLUSIONS
Both small doses intrathecal morphine of 0.1 mg and 0.2 mg provided adequate analgesia and patient satisfaction postoperatively with same incidences of side effects.

Keyword

Cesarean section; morphine; spinal analgesia

MeSH Terms

Analgesia*
Bupivacaine
Cesarean Section
Female
Fentanyl
Glucose
Humans
Incidence
Morphine*
Nalbuphine
Nausea
Patient Satisfaction
Pregnancy
Pruritus
Vomiting
Bupivacaine
Fentanyl
Glucose
Morphine
Nalbuphine