Korean J Anesthesiol.  1985 Sep;18(3):280-285.

Treatment of Urinary Rstsntion due to Intrathecal Injection of Morphine

• Kim YJ
• Kim IS
• Chung KS

Abstract

Intrathecal injection of morphine is widely used for relief of postoperative pain and the method is generally considered to provide excellent analgesia. Howerver adverse side effects such as respiratory depression, pruritus, vomiting and urinary retention occur following intrathecal injection of morphine. Among the side effects, urinary retention is destressing and troublesome. We have studied the effects of naloxone and neostigmine on urinary retention following intrathecal injection of morphine for the management of postoperative pain in 60 cases. The results were as follows. 1) Mean duration of urinary retention following intrathecal injection of morphine was 24.1+/-7.4 hours. 2) There was no statistical effect of neostigmine 1.0 mg i.m. in treating urinary retention due to intrathecal injection of morphine. 3) Single or repeated intravenous injections of naloxone were successful in treating urinary retention following intrathecal injection of mrphine. To treat urinary retention, a single dose of 0.8mg naloxone was more effective than a single dose of 0.4mg naloxone.

MeSH Terms

Analgesia
Injections, Intravenous
Injections, Spinal*
Morphine*
Naloxone
Neostigmine
Pain, Postoperative
Pruritus
Respiratory Insufficiency
Urinary Retention
Vomiting
Morphine
Naloxone
Neostigmine