Korean J Anesthesiol.  2001 Dec;41(6):S39-S42. 10.4097/kjae.2001.41.6.S39.

Acute Dystonia by Droperidol during Intravenous Patient-Controlled Analgesia in Children

• Park CK
• Choi HY
• Oh IY
• Kim MS

• KMID: 2091657
• DOI: http://doi.org/10.4097/kjae.2001.41.6.S39

Abstract

Patient-controlled analgesia (PCA) is an important means for postoperative analgesia with parenteral opioids. However, postoperative nausea and vomiting (PONV) remains a major complication with a PCA system. Droperidol is used in PCA to prevent PONV. Extrapyramidal reactions by droperidol are, however, occasionally induced. We describe two cases of severe extrapyramidal hypertonic syndrome with an IV administration of droperidol in PCA in two children, following orthopedic surgery. One patient showed a hypertonic syndrome 20 minutes after receiving droperidol 1.0 mg IV and the symptoms persisted for nearly 12 h without prescription. Another patient revealed an acute rigidity 19 h after the beginning of PCA and was treated with an IM administration of midazolam 2 mg successfully.

Keyword

Analgesics: fentanyl; Antiemetics: droperidol; Complication: dystonia

MeSH Terms

Analgesia
Analgesia, Patient-Controlled*
Analgesics, Opioid
Child*
Droperidol*
Dystonia*
Humans
Midazolam
Orthopedics
Passive Cutaneous Anaphylaxis
Postoperative Nausea and Vomiting
Prescriptions
Analgesics, Opioid
Droperidol
Midazolam