Korean J Dermatol.  2013 Feb;51(2):135-139.

A Case of Cutaneous Scedosporium apiospermum Infection Successfully Treated with Voriconazole

Affiliations
  • 1Department of Dermatology, Cheonan Hospital, College of Medicine, Soonchunhyang University, Cheonan, Korea. dermsung@schmc.ac.kr
  • 2Department of Laboratory Medicine, Cheonan Hospital, College of Medicine, Soonchunhyang University, Cheonan, Korea.

Abstract

Scedosporium apiospermum, an asexual state of Pseudallescheria boydii, is a widely distributed mould that can be found in the soil, manure, stagnant water and decaying vegetation. It has become an emerging pathogen among immunosuppressed patients but it can also cause infections in immunocompetent patients by penetrating trauma. This fungus is a classical cause of mycetoma and the localized skin infections caused by this mould are much rarer than mycetoma. We report a case of cutaneous S. apiospermum infection in a 79-year-old woman. She had erythematous plaque with crust and violaceous supprative nodules on the right forearm. The culture from pus showed typical white to gray colored cottony colonies of S. apiospermum. Treatment was started with voriconazole effectively. Skin lesions completely cured with no reccurence. Thus, voriconazole shows to be an effective treatment for Scedosporium infection.

Keyword

Scedosporium apiospermum; Skin infection; Voriconazole

MeSH Terms

Female
Forearm
Fungi
Humans
Manure
Mycetoma
Pseudallescheria
Pyrimidines
Scedosporium
Skin
Soil
Suppuration
Triazoles
Manure
Pyrimidines
Soil
Triazoles
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