Korean J Med Mycol.  2008 Dec;13(4):187-191.

A Case of Skin Infection due to Scedosporium apiospermum Treated with Voriconazole

Affiliations
  • 1Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea.
  • 2Department of Laboratory Medicine, Gyeongsang National University School of Medicine, Jinju, Korea. cadevar@yahoo.co.kr
  • 3Gyeongsang Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.

Abstract

Scedosporium(S.) apiospermum has been isolated from polluted water, soil, sewage and potted plants in a hospital with low virulence. The localized skin infection due to S. apiospermum is rare and usually results from traumatic implantation of contaminated material due to a penetrating injury. We report a case of skin infection due to S. apiospermum in a 78-year-old female. She had multiple nodules, pustules and exudative ulcerative lesions at the right forearm. Cultured isolation for definitive diagnosis showed typical S. apiospermum. Treatment was started with itraconazole effectively, but skin lesions were recurred after 4 months, and then cured with voriconazole with no recurrence.

Keyword

Scedosporium apiospermum; Skin infection; Itraconazole; Voriconazole

MeSH Terms

Aged
Female
Forearm
Humans
Itraconazole
Pyrimidines
Recurrence
Scedosporium
Sewage
Skin
Soil
Triazoles
Ulcer
Itraconazole
Pyrimidines
Sewage
Soil
Triazoles
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