Korean J Dermatol.
2000 Jan;38(1):90-94.
A Case of Herpes Gestationis Treated with Cyclosporine
- Affiliations
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- 1Department of Dermatology, College of Medicine, The Catholic University of Korea.
- 2Department of Dermatology, College of Medicine, Hanyang University, Seoul, Korea.
Abstract
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Herpes gestationis is a rare pregnancy-associated autoimmune bullous disease resembling bullous pemphigoid in both clinical and immunohistopathological aspects. Generally it may be improved spontaneously or easily controlled by topical or low-dose corticosteroid. Very rarely, however, severe and long-standing cases that did not respond to high-dose corticosteoid therapy were reported. We present a case of an unusual severe herpes gestationis in a 26-year-old woman that was resistant to high-dose corticosteroid and/or dapsone therapy. But the lesions responded dramatically to low-dose cyclosporine.