Korean J Dermatol.  1995 Aug;33(4):727-732.

A Case of Herpes Gestationis

Abstract

Herpes gestationis(HG) characterized by the development of autoantibodies to the basement membrane is a pruritic bullous dermatosis of pregnancy and the postpartum period. HG is diag nosed on the basis of clinical findings, and a direct or indirect immunofluorescent test including an assaying for the denmonstration of IgG autoantibody in the serum. We report a case of herpes gestationis in Korea which showed a typical clinical and histopathologic findings accuring in a 30-year old primiparous patient. We could confirm the diagnosis in this case by in vitro C3 staining, and immunoblot analysis which revealed the presence of antibodies in her sertim against 180kD antigen of epidermal protein.

Keyword

Autoantibody; Elerpes gestationis; lmmunoblot analysis

MeSH Terms

Adult
Antibodies
Autoantibodies
Basement Membrane
Diagnosis
Female
Humans
Immunoglobulin G
Korea
Nose
Pemphigoid Gestationis*
Postpartum Period
Pregnancy
Skin Diseases
Antibodies
Autoantibodies
Immunoglobulin G
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