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Comparative Study of Quality of Life in Patients with Scalp Psoriasis Treated Using Topical Steroid Alone vs. Topical Steroid Combined with Cyclosporine

Kim M, Yang S, Kim BR, Youn SW

  • KMID: 2465915
  • Korean J Dermatol.
  • 2019 Nov;57(9):513-518.
BACKGROUND: Scalp psoriasis severely affects patients' quality of life, and patients may occasionally be refractory to topical steroid application. Although systemic therapy combined with topical steroid application is recommended for...
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Cyclosporin A aggravates hydrogen peroxide-induced cell death in kidney proximal tubule epithelial cells

Moon D, Kim J

Cyclosporin A (CsA) does not only exert a toxic effect on kidney parenchymal cells, but also protects them against necrotic cell death by inhibiting opening of mitochondrial permeability transition pore....
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Development of a physiologically-based pharmacokinetic model for cyclosporine in Asian children with renal impairment

Yoon S, Yi S, Rhee SJ, Lee HA, Kim Y, Yu KS, Chung JY

This study aimed to assess the pharmacokinetics of cyclosporine A (CsA) in Asian children with renal impairment (RI) by developing a physiologically-based pharmacokinetic (PBPK) model with Simcyp Simulator. The PBPK...
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Factors Predicting the Response to Cyclosporin Treatment in Patients With Chronic Spontaneous Urticaria: A Systematic Review

Kulthanan , Subchookul C, Hunnangkul S, Chularojanamontri L, Tuchinda P

PURPOSE: This study aimed to systemically review literature relating to factors that could potentially predict a favorable response to cyclosporine A (CsA) treatment for chronic spontaneous urticaria (CSU). METHODS: A systematic...
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Efficacy of Topical Cyclosporine Nanoemulsion 0.05% Compared with Topical Cyclosporine Emulsion 0.05% and Diquafosol 3% in Dry Eye

Park CH, Kim MK, Kim EC, Kim JY, Kim TI, Kim HK, Song JS, Yoon KC, Lee DH, Lee HK, Chung TY, Choi CY, Kim HS

PURPOSE: To evaluate the efficacy and safety of cyclosporine nanoemulsion 0.05% compared to cyclosporine emulsion 0.05% and diquafosol sodium 3%. METHODS: This was a multicenter, randomized, evaluator-masked, active control, parallel, phase...
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Comparative Study of Clinical Characteristics according to Therapeutic Efficacy and Drug Survival of Cyclosporine or Methotrexate in Psoriasis Vulgaris

Lee HS, Kwon SH, Lee ES

No abstract available.
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Performance Evaluation of the ARCHITECT i2000 for the Determination of Whole Blood Cyclosporin A and Tacrolimus

Lim M, Lee YW

Maintaining immunosuppressant concentrations within the therapeutic range in organ recipients requires regular monitoring. The blood concentrations of immunosuppressants are routinely measured using one of several automated immunoassays, such as chemiluminescence...
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Unilateral Deep Peroneal Neuropathy during Cyclosporine Therapy

Yoo JS, Kwon HS, Koh SH, Lee KY, Lee YJ, Choi H, Chung J

No abstract available.
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Comparison of Efficacy and Sensation of Instillation between 0.05% Cyclosporine Nanoemulsion and Microemulsion Type

Shin EH, Lim DH, Yang CM, Chung TY

PURPOSE: To evaluate and compare the efficacy and sensation of instillation between 0.05% cyclosporine nanoemulsion group and microemulsion group. METHODS: This is a double-blind, prospective randomized clinical trial. Patients had 2...
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Low-dose Acitretin and Cyclosporine Combination Therapy in Patients with Psoriasis: A Retrospective Analysis of 37 Cases

Gwak MJ, Kang IH, Shin MK, Kim NI

  • KMID: 2437069
  • Korean J Dermatol.
  • 2018 Dec;56(10):658-659.
No abstract available.
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Monitoring of Mycophenolic Acid Trough Concentration in Kidney Transplant under Cyclosporine Is Beneficial in Reducing Acute Rejection within 1 Year

Rhu J, Lee KW, Park JB, Kim SJ

BACKGROUND: This study was designed to analyze the clinical usefulness of mycophenolic acid trough concentration monitoring in kidney transplantation patients who were maintained with cyclosporine. METHODS: The data of patients who...
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Protective Effect of Right Ventricular Mitochondrial Damage by Cyclosporine A in Monocrotaline-induced Pulmonary Hypertension

Lee DS, Jung YW

BACKGROUND AND OBJECTIVES: Mitochondria play a key role in the pathophysiology of heart failure and mitochondrial permeability transition pore (MPTP) play a critical role in cell death and a critical...
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Clinical Efficacy of Oral Cyclosporine on Intractable Hand Eczema: A Retrospective Review of 16 Cases

Kim HL, Jung HJ, Park MY, Youn JI, Ahn JY

No abstract available.
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A Novel Method to Study the Effects of Cyclosporine on Gingival Overgrowth in Children

Han K, Kim J

Previous studies to elucidate the etiology of cyclosporine(Cs)-induced gingival overgrowth in children have not completely excluded all factors that may cause differences among individuals. This study examined the effect of...
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Risk Factors Affecting Adverse Effects of Cyclosporine A in a Real-World Psoriasis Treatment

Kim BR, Yang S, Doh EJ, Choi CW, Youn SW

BACKGROUND: No study to date has focused on the changes in laboratory test results and related risk factors in patients with psoriasis treated with prolonged Cyclosporine A (CsA) therapy. OBJECTIVE: The...
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Multi-center Performance Evaluations of Tacrolimus and Cyclosporine Electrochemiluminescence Immunoassays in the Asia-Pacific Region

Qin X, Rui J, Xia Y, Mu H, Song SH, Raja Aziddin RE, Miles G, Sun Y, Chun S

BACKGROUND: The immunosuppressant drugs (ISDs), tacrolimus and cyclosporine, are vital for solid organ transplant patients to prevent rejection. However, toxicity is a concern, and absorption is highly variable across patients;...
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The Effect of Mycophenolate Mofetil versus Cyclosporine as Combination Therapy with Low Dose Corticosteroids in High-risk Patients with Idiopathic Membranous Nephropathy: a Multicenter Randomized Trial

Choi JY, Kim DK, Kim YW, Yoo TH, Lee JP, Chung HC, Cho KH, An WS, Lee DH, Jung HY, Cho JH, Kim CD, Kim YL, Park SH

BACKGROUND: Appropriate immunosuppressive therapy for patients with idiopathic membranous nephropathy (MN) remains controversial. The effect of mycophenolate mofetil (MMF) versus cyclosporine (CsA) combined with low-dose corticosteroids was evaluated in patients...
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Effectiveness of Cyclosporine in a 10-year-old Girl with C3 Glomerulopathy

Jang KM, Park YH

C3 glomerulopathy (C3G) is a recently defined pathological entity characterized by C3 accumulation with absent or scant immunoglobulin deposition, leading to variable glomerular inflammation. The clinical presentation of patients with...
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Therapeutic Efficacy of Combination Therapy Using Oral Cyclosporine with a Dietary Supplement (Pantogar®) in Twenty-Nail Dystrophy

Oh SJ, Kim JE, Ko JY, Ro YS

BACKGROUND: Twenty-nail dystrophy (TND) is an acquired idiopathic disease characterized by dull, thin, lusterless, and fragile nails with fissuring, small regular pits, and excessive longitudinal ridging. Although various treatment modalities...
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A Case of Widespread Scleredema Treated with Cyclosporine and Steroid

Kim HW, Choi MW, Son SJ, Lee JH, Han TY

  • KMID: 2396222
  • Korean J Dermatol.
  • 2017 Sep;55(8):537-538.
No abstract available.
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