- Acute Severe Ulcerative Colitis: Optimal Strategies for Drug Therapy
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Nakase H
- KMID: 2538156
- Gut Liver.
- 2023 Jan;17(1):49-57.
- doi: 10.5009/gnl220017
Acute severe ulcerative colitis (ASUC) is a life-threatening medical emergency with considerable morbidity (30% to 40%). Patients with ASUC require hospitalization for prompt medical treatment, and colectomy is considered if... -
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- Two Cases of Pityriasis Rubra Pilaris after Cyclosporine Treatment
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Kim JS, Lee JS, Koo DW
- KMID: 2538566
- Korean J Dermatol.
- 2022 Dec;60(10):683-686.
Pityriasis rubra pilaris (PRP) is a rare chronic inflammatory papulosquamous disease of the skin. Its exact pathogenesis and incidence are not yet known. Clinically, it presents as palmoplantar keratoderma, hyperkeratotic... -
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- A Case of Rebound Phenomenon after Cessation of Cyclosporine for Guselkumab Therapy in Psoriasis
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Park SH, Jung SY
- KMID: 2538565
- Korean J Dermatol.
- 2022 Dec;60(10):679-682.
Cyclosporine is one of the main therapeutic agents for psoriasis. It is known that psoriasis relapses 2∼3 months after discontinuation of cyclosporine, and exacerbation due to abrupt discontinuation of cyclosporine... -
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- The Efficacies and Safeties of a 0.05% Cyclosporine Nanoemulsion and a 0.1% Cyclosporine Cationic Emulsion
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Ji M, Choi CY, Kim SJ, Jeong J
- KMID: 2534436
- J Korean Ophthalmol Soc.
- 2022 Oct;63(10):834-840.
- doi: 10.3341/jkos.2022.63.10.834
Purpose: We evaluated the efficacy and safety of a 0.05% cyclosporine ophthalmic nanoemulsion and a 0.1% cyclosporine ophthalmic cationic emulsion in patients with moderate-to-severe dry-eye syndrome. Methods: This was a multi-center,... -
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- Adverse Events and Safety of Oral Cyclosporine for Dermatoses among Children and Adolescents: A Single Center Study
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Kim YH, Han HJ, Kang HY, Park YJ, Choi JW
- KMID: 2534009
- Korean J Dermatol.
- 2022 Sep;60(8):483-490.
Background: Cyclosporine (CS) is widely used in various dermatological diseases, and its range of usage has been expanded to younger patients. However, data on the safety of CS in children... -
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- The Association between Cumulative Dose of Cyclosporine and Renal Function Abnormality in Dermatology Patients Managed with Low Dose Regimen
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Kim JW, Kim M, Kim BR, Youn SW
- KMID: 2518984
- Korean J Dermatol.
- 2021 Jul;59(6):426-433.
Background: Cyclosporine (CsA), an immunosuppressant that specifically regulates T-lymphocytes, has long been used in dermatology practice. However, nephrotoxicity, a well-known adverse effect associated with high-dose (≥5 mg/kg/d) and long-term administration... -
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- A Retrospective Analysis of the Factors Affecting the Treatment Outcomes of Cyclosporine in Patients with Psoriasis
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Choi YG, Lee HJ, Choi YJ, Kim WS, Lee GY
- KMID: 2516139
- Korean J Dermatol.
- 2021 May;59(4):266-276.
Background: Cyclosporine is an effective drug for the treatment of psoriasis. Nonetheless, little is known about the factors associated with its effectiveness. Objective: This study aimed to analyze the factors affecting... -
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- Omalizumab for Cyclosporine-resistant Chronic Spontaneous Urticaria: A Retrospective Study of a Single Center
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Kim HJ, Kim Wi, Shin K, Son JH, Lee WK, Kim HS, Kim B, Kim MB, Ko HC
- KMID: 2514427
- Korean J Dermatol.
- 2021 Mar;59(3):175-180.
Background: Cyclosporine is a recommended third-line treatment for chronic spontaneous urticaria (CSU) that is resistant to H1-antihistamines according to the EAACI/GA 2 LEN/EDF/WAO guidelines for management of urticaria. However, some... -
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- Therapeutic Outcomes of Long-term Low-dose Systemic Cyclosporine Treatment in Patients with Chronic Alopecia Areata
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Cho YR, Kim KH
- KMID: 2506580
- Korean J Dermatol.
- 2020 Sep;58(8):505-511.
Background: Alopecia areata (AA) is a T cell-mediated autoimmune disease. In patients with chronic AA, hair loss occurs because of the insidious destruction of the stem cells in the hair... -
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- Effect of Cyclosporine A-induced Senescence on Cultured Human Corneal Endothelial Cells
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Jang YK, Chung TY, Shin YJ
- KMID: 2506473
- J Korean Ophthalmol Soc.
- 2020 Sep;61(9):999-1009.
- doi: 10.3341/jkos.2020.61.9.999
Purpose: To investigate the in vitro effect of cyclosporine A (CsA)-induced senescence on human corneal endothelial cells (HCECs). Methods: HCECs were cultured and incubated with 0-100 µM CsA. Senescence-associated β–galactosidase (SA-β-gal)... -
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- Urinary Concentration Defect and Renal Glycosuria in Cyclosporine-treated Rats
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Lee JH, Kim SA, Jo CH, Lee CH, Kim GH
- KMID: 2503008
- Electrolyte Blood Press.
- 2020 Jun;18(1):1-9.
- doi: 10.5049/EBP.2020.18.1.1
Background: Urinary concentration impairment is a major feature of cyclosporine nephrotoxicity. Methods: We explored two possible mechanisms that may underlie cyclosporineinduced polyuria; water, and/or osmotic diuresis. Cyclosporine was subcutaneously injected to... -
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- Characteristics and Management of Cyclosporine-associated Adverse Gastrointestinal Events
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Koh WS, Ko YW, Kim JE, Ko JY, Ro YS
- KMID: 2470214
- Korean J Dermatol.
- 2019 Dec;57(10):608-616.
BACKGROUND: Cyclosporine (CS) is widely used to treat various skin diseases. Gastrointestinal (GI) discomfort is the most common adverse effect of orally administered CS for dermatologic indications. However, few studies... -
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- Comparative Study of Quality of Life in Patients with Scalp Psoriasis Treated Using Topical Steroid Alone vs. Topical Steroid Combined with Cyclosporine
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Kim M, Yang S, Kim BR, Youn SW
- KMID: 2465915
- Korean J Dermatol.
- 2019 Nov;57(9):513-518.
BACKGROUND: Scalp psoriasis severely affects patients' quality of life, and patients may occasionally be refractory to topical steroid application. Although systemic therapy combined with topical steroid application is recommended for... -
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- Effectiveness of Cyclosporine-steroid Treatment after Cataract Surgery according to Dry Eye Severity
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Park JY, Yang SC, Park YM, Lee JE, Park CY, Lee JS
- KMID: 2459125
- J Korean Ophthalmol Soc.
- 2019 Sep;60(9):821-828.
- doi: 10.3341/jkos.2019.60.9.821
PURPOSE: To evaluate the effectiveness of topically administered 0.05% cyclosporine combined with a topical steroid in the early postoperative period after cataract surgery, and to compare the therapeutic efficacy according... -
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- Development of a physiologically-based pharmacokinetic model for cyclosporine in Asian children with renal impairment
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Yoon S, Yi S, Rhee SJ, Lee HA, Kim Y, Yu KS, Chung JY
- KMID: 2458950
- Transl Clin Pharmacol.
- 2019 Sep;27(3):107-114.
- doi: 10.12793/tcp.2019.27.3.107
This study aimed to assess the pharmacokinetics of cyclosporine A (CsA) in Asian children with renal impairment (RI) by developing a physiologically-based pharmacokinetic (PBPK) model with Simcyp Simulator. The PBPK... -
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- Factors Predicting the Response to Cyclosporin Treatment in Patients With Chronic Spontaneous Urticaria: A Systematic Review
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Kulthanan , Subchookul C, Hunnangkul S, Chularojanamontri L, Tuchinda P
- KMID: 2452762
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):736-755.
- doi: 10.4168/aair.2019.11.5.736
PURPOSE: This study aimed to systemically review literature relating to factors that could potentially predict a favorable response to cyclosporine A (CsA) treatment for chronic spontaneous urticaria (CSU). METHODS: A systematic... -
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- Efficacy of Topical Cyclosporine Nanoemulsion 0.05% Compared with Topical Cyclosporine Emulsion 0.05% and Diquafosol 3% in Dry Eye
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Park CH, Kim MK, Kim EC, Kim JY, Kim TI, Kim HK, Song JS, Yoon KC, Lee DH, Lee HK, Chung TY, Choi CY, Kim HS
- KMID: 2454775
- Korean J Ophthalmol.
- 2019 Aug;33(4):343-352.
- doi: 10.3341/kjo.2018.0116
PURPOSE: To evaluate the efficacy and safety of cyclosporine nanoemulsion 0.05% compared to cyclosporine emulsion 0.05% and diquafosol sodium 3%. METHODS: This was a multicenter, randomized, evaluator-masked, active control, parallel, phase... -
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- Unilateral Deep Peroneal Neuropathy during Cyclosporine Therapy
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Yoo JS, Kwon HS, Koh SH, Lee KY, Lee YJ, Choi H, Chung J
- KMID: 2454850
- J Korean Neurol Assoc.
- 2019 May;37(2):195-197.
- doi: 10.17340/jkna.2019.2.15
No abstract available. -
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- Comparison of Efficacy and Sensation of Instillation between 0.05% Cyclosporine Nanoemulsion and Microemulsion Type
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Shin EH, Lim DH, Yang CM, Chung TY
- KMID: 2440451
- J Korean Ophthalmol Soc.
- 2019 Mar;60(3):239-245.
- doi: 10.3341/jkos.2019.60.3.239
PURPOSE: To evaluate and compare the efficacy and sensation of instillation between 0.05% cyclosporine nanoemulsion group and microemulsion group. METHODS: This is a double-blind, prospective randomized clinical trial. Patients had 2... -
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- Low-dose Acitretin and Cyclosporine Combination Therapy in Patients with Psoriasis: A Retrospective Analysis of 37 Cases
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Gwak MJ, Kang IH, Shin MK, Kim NI
- KMID: 2437069
- Korean J Dermatol.
- 2018 Dec;56(10):658-659.
No abstract available. -
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