Korean J Nephrol.
2004 May;23(3):509-513.
A Case of Rhabdomyolysis and Acute Renal Failure Associated with Mitochondrial Myopathy
- Affiliations
-
- 1Department of Internal Medicine, Hanil Hospital, Seoul, Korea. manitol@medigate.net
- 2Department of Neurology, Hanil Hospital, Seoul, Korea.
Abstract
- Mitochondrial myopathies are diseases caused by defects in metabolic pathway of mitochondria. Mitochondrial myopathy is known as one of the causes of recurrent myoglobinuria, while clinically, rarely causes acute renal failure requiring medical treatments. We report a case of rhabdomyolysis and acute renal failure associated with mitochondrial myopathy. A 58-year-old male was presented with dyspnea and hypotensive shock. The patient had a history of recurrent dark colored urine and cramping leg pain after prolonged fasting. Laboratory findings showed hyperkalemia, azotemia, metabolic acidosis, and elevated AST, ALT, and creatinine kinase. He had no history of trauma or medication. Muscle biopsy showed "ragged red fibers" in modified Gomori staining. On electron microscope, increased number of mitochondria and abnormal mitochondria were seen. He received hemodialysis and his renal function recovered after 1 month.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A case of myoglobinuric acute renal failure due to polymyositis in patient with chronic hepatitis C
- A Case of Rhabdomyolysis and Acute Renal Failure Associated with Primary Hypothyroidism
- A Case of Acute Renal Failure Caused by Rhabdomyolysis due to Hyperosmolar Nonketotic Coma in Children
- Thrombotic Thrombocytopenic Purpura and Rhabdomyolysis Associated With Acute Renal Failure in Hypothyroidism
- A Case with Diabetic Hyperosmolar Nonketotic Coma Who Developed Acute Renal Failure Secondary to Rhabdomyolysis
