Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

605 results
Display

Mitochondrial Quality Control in the Heart: New Drug Targets for Cardiovascular Disease

Oh CM, Ryu D, Cho S, Jang Y

Despite considerable efforts to prevent and treat cardiovascular disease (CVD), it has become the leading cause of death worldwide. Cardiac mitochondria are crucial cell organelles responsible for creating energy-rich ATP...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mitochondrial Mechanisms in Diabetic Cardiomyopathy

Gollmer J, Zirlik A, Bugger H

Mitochondrial medicine is increasingly discussed as a promising therapeutic approach, given that mitochondrial defects are thought to contribute to many prevalent diseases and their complications. In individuals with diabetes mellitus...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Ceramides: Nutrient Signals that Drive Hepatosteatosis

Summers SA

Ceramides are minor components of the hepatic lipidome that have major effects on liver function. These products of lipid and protein metabolism accumulate when the energy needs of the hepatocyte...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification and Characterization of Two New S-Adenosylmethionine-Dependent Methyltransferase Encoding Genes Suggested Their Involvement in Stipe Elongation of Flammulina velutipes

Huang Q, Mukhtar I, Zhang Y, Wei Z, Han X, Huang R, Yan J, Xie B

Two new SAM-dependent methyltransferase encoding genes (fvsmt1 and fvsmt2) were identified from the genome of Flammulina velutipes. In order to make a comprehensive characterization of both genes, we performed in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Anti-tumor activity and mitochondrial stability of disulfiram in HL-60 cells

Disulfiram (DSF) is a member of the dithiocarbamate family that can bind copper. Recent studies have shown that DSF has anti-cancer activities, but the mechanism has not been clarified. Therefore,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Etoposide Induces Mitochondrial Dysfunction and Cellular Senescence in Primary Cultured Rat Astrocytes

Bang M, Kim DG, Gonzales E, Kwon KJ, Shin CY

Brain aging is an inevitable process characterized by structural and functional changes and is a major risk factor for neurodegenerative diseases. Most brain aging studies are focused on neurons and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genetic Basis of Steroid Resistant Nephrotic Syndrome

Park E

Steroid-resistant nephrotic syndrome (SRNS) has long been a challenge for clinicians due to its poor responsiveness to immunosuppressants, and rapid progression to end-stage renal disease. Identifying a monogenic cause for...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mitochondrial DNA Sequence Variability of Spirometra Species in Asian Countries

Jeon HK, Eom KS

Mitochondrial DNA sequence variability of Spirometra erinaceieuropaei in GenBank was observed by reinvestigation of mitochondrial cox1 and cytb sequences. The DNA sequences were analyzed in this study, comprising complete DNA...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Cholesterol Metabolism in the Brain and Its Association with Parkinson's Disease

Jin U, Park SJ, Park SM

Parkinson's disease (PD) is the second most progressive neurodegenerative disorder of the aging population after Alzheimer’s disease (AD). Defects in the lysosomal systems and mitochondria have been suspected to cause...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Ubiquitin E3 Ligase Pellino-1 Inhibits IL-10-mediated M2c Polarization of Macrophages, Thereby Suppressing Tumor Growth

Kim D, Koh J, Ko JS, Kim HY, Lee H, Chung DH

Pellino-1 is a ubiquitin (Ub) E3 ligase that plays a role in M1, but not M2a polarization of macrophages. However, it is unknown whether Pellino-1 regulates IL-10-mediated M2c polarization of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mitochondrial Toxins and Healthy Lifestyle Meet at the Crossroad of Hormesis

Lee YM, Lee DH

Mitochondrial function is crucial for the maintenance of cellular homeostasis under physiological and stress conditions. Thus, chronic exposure to environmental chemicals that affect mitochondrial function can have harmful effects on...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Regulation of Systemic Glucose Homeostasis by T Helper Type 2 Cytokines

Kang YE, Kim HJ, Shong M

Obesity results in an inflammatory microenvironment in adipose tissue, leading to the deterioration of tissue protective mechanisms. Although recent studies suggested the importance of type 2 immunity in an anti-inflammatory...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Reactive Oxygen Species Modulator 1 (ROMO1), a New Potential Target for Cancer Diagnosis and Treatment

Amini MA, Talebi SS, Karimi J

Today, the incidence of cancer in the world is rising, and it is expected that in the next several decades, the number of people suffering from cancer or (the cancer...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pseudolaric acid B inhibits PAX2 expression through Wnt signaling and induces BAX expression, therefore promoting apoptosis in HeLa cervical cancer cells

Guan D, Li C, Lv X, Yang Y

OBJECTIVES: Pseudolaric acid B (PAB) has been shown to inhibit the growth of various tumor cells, but the molecular details of its function are still unknown. This study investigated the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Asiatic Acid Protects Dopaminergic Neurons from Neuroinflammation by Suppressing Mitochondrial ROS Production

Chen D, Zhang XY, Sun J, Cong QJ, Chen WX, Ahsan HM, Gao J, Qian JJ

This study sought to evaluate the effects of Asiatic acid in LPS-induced BV2 microglia cells and 1-methyl-4-phenyl-pyridine (MPP⁺)-induced SH-SY5Y cells, to investigate the potential anti-inflammatory mechanisms of Asiatic acid in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Profiling of remote skeletal muscle gene changes resulting from stimulation of atopic dermatitis disease in NC/Nga mouse model

Lee D, Seo Y, Kim YW, Kim S, Choi J, Moon SH, Bae H, Kim HS, Kim H, Kim JH, Kim TY, Kim E, Yim S, Lim I, Bang H, Kim JH, Ko JH

Although atopic dermatitis (AD) is known to be a representative skin disorder, it also affects the systemic immune response. In a recent study, myoblasts were shown to be involved in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mitochondrial Dysfunction in Adipocytes as a Primary Cause of Adipose Tissue Inflammation

Woo CY, Jang JE, Lee SE, Koh EH, Lee KU

Adipose tissue inflammation is considered a major contributing factor in the development of obesity-associated insulin resistance and cardiovascular diseases. However, the cause of adipose tissue inflammation is presently unclear. The...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Evaluation of bioenergetic and mitochondrial function in liver transplantation

Martins RM, Teodoro JS, Furtado E, Rolo AP, Palmeira C, Tralhão J

BACKGROUND/AIMS: We measured changes in mitochondrial function and bioenergetics that occur during ischemia/reperfusion in fresh liver samples of patients undergoing liver transplantation. These variations correlated with markers of liver function...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson's Disease: Drp1 and CDK5/p25 Signaling

Park J, Seo J, Won J, Yeo HG, Ahn YJ, Kim K, Jin YB, Koo BS, Lim KS, Jeong KJ, Kang P, Lee HY, Baek SH, Jeon CY, Hong JJ, Huh JW, Kim YH, Park SJ, Kim SU, Lee DS, Lee SR, Lee Y

Mitochondria continuously fuse and divide to maintain homeostasis. An impairment in the balance between the fusion and fission processes can trigger mitochondrial dysfunction. Accumulating evidence suggests that mitochondrial dysfunction is...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Induction of Melanoma Cell-Selective Apoptosis Using Anti-HER2 Antibody-Conjugated Gold Nanoparticles

Jeon HJ, Choi BB, Park KH, Hwang DS, Kim UK, Kim GC

PURPOSE: This study was conducted to verify the induction and mechanism of selective apoptosis in G361 melanoma cells using anti-HER2 antibody-conjugated gold nanoparticles (GNP-HER2). MATERIALS AND METHODS: Following GNP-HER2 treatment of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr