Korean J Med.
1999 May;56(5):636-640.
A case of myoglobinuric acute renal failure due to polymyositis in patient with chronic hepatitis C
- Affiliations
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- 1Department of Internal Medicine, Sanggye Paik Hospital, Inje University, Seoul, Korea.
Abstract
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A 73-year-old woman with chronic hepatitis C was hospitalized with proximal muscle weakness and
generalized muscle pain. The patient was diagnosed as rhabdomyolysis with myoglobinuric acute
renal failure. But there was no history of muscle compression, ingestion of drugs which can
cause rhabdomyolysis, or alcohol abuse. The initial clinical features and laboratory findings
showed no evidence of infectious myopathy or electrolyte abnormality. The electromyography and
muscle biopsy was performed and polymyositis was diagnosed. Polymyositis, an idiopathic
inflammatory myopathy, can cause rhabdomyolysis, but myoglobinuric acute renal failure due to
polymyositis is very rare. We report a case of myoglobinuric acute renal failure caused by
polymyositis with review of the literatures.