Korean J Med.  2011 Jan;80(1):87-91.

Pathological Findings of a Renal Biopsy Showing Chronic Hepatitis B in A Patient with Acute Hepatitis A

Affiliations
  • 1Department of Internal Medicine, Sun General Hospital, Daejeon, Korea. hyounmokang@hanmail.net
  • 2Department of Pathology, Chungnam National University College of Medicine, Daejeon, Korea.

Abstract

Hepatitis A is usually a self-limited liver disease that is treated conservatively. Acute renal injury complicating acute hepatitis A in the absence of fulminant hepatic failure is rare. We experienced a 33-year-old man who was healthy, and did not know that he was a hepatitis B virus (HBV)carrier with non-fulminant hepatitis A. He developed an acute kidney injury that necessitated dialysis therapy and a renal biopsy. He recovered within about 1 month. Pathologically, the renal biopsy showed acute tubular necrosis. It also showed IgA nephropathy and mesangium proliferation with glomerular nephritis, which are seen in chronic viral hepatitis B. We describe the association of acute hepatitis A with acute kidney injury and report the pathological findings of a renal biopsy related to chronic hepatitis B in an acute hepatitis A patient discovered by chance.

Keyword

Hepatitis A; Acute kidney injury; Chronic hepatitis B

MeSH Terms

Acute Kidney Injury
Adult
Biopsy
Dialysis
Glomerulonephritis, IGA
Hepatitis
Hepatitis A
Hepatitis B
Hepatitis B virus
Hepatitis B, Chronic
Hepatitis, Chronic
Humans
Liver Diseases
Liver Failure, Acute
Necrosis
Nephritis
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