Korean J Pathol.
1999 Aug;33(8):620-623.
Tracheobronchial Aspergillosis An autopsy case report
- Affiliations
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- 1 Section of Histopathology, Department of Forensic Medicine, National Institute of Scientific Investigation, Seoul 158-097, Korea.
Abstract
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Tracheobronchial aspergillosis is an unusual form of invasive aspergillosis
characterized by noninvasive or only superficially invasive tracheobronchitis with a
propensity for dissemination. We report a two-year-old male who suddenly died of
respiratory failure. Postmortem examination revealed a pseudomembrane covering the
mucosa of larynx, trachea and bronchial tree of both lungs. This pseudomembrane was
composed predominantly of Aspergillus hyphae. There was transmural necrotizing
bronchitis with fungal invasion to the narrow zone of peribronchial tissue, and
dissemination to the stomach and kidney. This form of pulmonary aspergillosis had not
been reported in this country.