Infect Chemother.  2011 Feb;43(1):76-81. 10.3947/ic.2011.43.1.76.

Invasive Tracheobronchial Aspergillosis : Case Reports and a Literature Review

• Choi JK
• No JH
• Lee BH
• Yun JS
• Kim SH
• Kwon JC
• Hong JH
• Lee GJ
• Park SH
• Choi SM
• Lee DG
• Choi JH
• Yoo JH

• KMID: 2170339
• DOI: http://doi.org/10.3947/ic.2011.43.1.76

Abstract

Invasive tracheobronchial aspergillosis (iTBA) is an uncommon clinical manifestation of invasive aspergillosis and this is usually limited to the large airways. Its pathophysiology and clinical features are obscure, but some fatal cases of iTBA in immunocompetent patients have also been reported. We describe 4 cases of iTBA in the patients with hematologic malignancies, that was early diagnosed by bronchoscopy, a computed tomography and successfully treated by proper antifungal treatment. And we also review the cases of iTBA reported in Korea.

Keyword

Aspergillosis; Trachea; Bronchi; Korea

MeSH Terms

Aspergillosis
Bronchi
Bronchoscopy
Hematologic Neoplasms
Humans
Korea
Trachea

Figure

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  Figure 1 Bronchoscopy shows obstruction of the right main bronchus by endobronchial polypoid

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  Figure 2 CT scan of the chest. Figure 2A shows nodular thickening and enhancement of the anterior tracheal wall (case 2) and figure 2B shows peripheral rim enhancement and luminal narrowing of the right main bronchus and the right upper bronchus (case 3).

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