Korean J Intern Med.  2006 Dec;21(4):279-282. 10.3904/kjim.2006.21.4.279.

Case of Pseudomembranous Necrotizing Tracheobronchial Aspergillosis in an Immunocompetent Host

• Oh HJ
• Kim HR
• Hwang KE
• Kim SY
• Ahn SH
• Yang SH
• Jeong ET

• KMID: 759866
• DOI: http://doi.org/10.3904/kjim.2006.21.4.279

Abstract

A 44-year-old Korean male died of rapidly progressive respiratory failure and refractory hypoxemia in 8 days after being admitted with a fever and dyspnea. The patient was diagnosed with pseudomembranous necrotizing tracheobronchial aspergillosis by fibroptic bronchoscopy and it was not related to an invasion of the pulmonary parenchyma. To the best of our knowledge, this case represents a patient with pseudomembranous necrotizing tracheobronchial aspergillosis that developed in an immunocompetent host, rapidly resulting in airway obstruction with acute respiratory failure and refractory hypoxemia without an invasion of the pulmonary parenchyma.

Keyword

Aspergillosis; Immunocompetence; Respiratory insufficiency

MeSH Terms

Tracheitis/complications/diagnosis/*immunology
Tomography, X-Ray Computed
Respiratory Insufficiency/diagnosis/etiology
Necrosis/complications/diagnosis/immunology
Male
*Immunocompromised Host
Humans
Fatal Outcome
Diagnosis, Differential
Bronchoscopy
Bronchitis/diagnosis/*immunology/radiography
Biopsy
Aspergillosis/complications/diagnosis/*immunology
Adult