J Korean Neurosurg Soc.  1997 Jul;26(7):940-945.

Factors Influencing the Development of Peritumoral Brain Edema in Menigiomas

• Kim IS
• Kim HD
• Kim KU
• Shin HC
• Choin HJ
• Kim KH

Abstract

In a series of 43 patients with intracranial meningioma, we retrospectively analysed factors influencing the development of peritumoral brain edema(PTBE). The extent of this was measured by the Edema Index(EI), obtained from the size of the meningioma and associated PTBE on a T2-weighted magnetic resonance image. We evaluated the relationship between EI and certain factors that may play a role in the development of PTBE ; namely age, size, location, and histology of the tumor, and its vascular supply(intrinsic cerebral artery or meningeal artery). Tumors in the frontal and sphenoid ridge regions tended to be associated with more extensive PTBE than these in the parietal, occipital, and infratentorial regions(p<0.05). In particular, the extent of infratentorial meningioma-associated PTBE tended to be slight. Histologically, PTBE associated with meningotheliomatous and transitional meningiomas tended to be more extensive than that associated with the fibroblastic meningiomas(p<0.05). On angiography, it was seen that for meningiomas supplied by intrinsic cerebral artery(internal carotid or veterbral artery only, or in conjunction with the meningeal artery), correlation with severe PTBE was higher than for those supplied by the meningeal artery only(p<0.05). We concluded, therefore, that location, histology, and vascular supply from the intrinsic cerebral arteries were the factors influencing PTBE.

Keyword

Edema index; Meningioma; Peritumoral brain edema; Vascular supply

MeSH Terms

Angiography
Arteries
Brain Edema*
Brain*
Cerebral Arteries
Edema
Fibroblasts
Humans
Meningeal Arteries
Meningioma
Rabeprazole
Retrospective Studies