Brain Tumor Res Treat.  2022 Oct;10(4):275-278. 10.14791/btrt.2022.0040.

Meningioma With Partial and Spontaneous Regression of Peritumoral Edema on Long-Term Follow Up

  • 1Department of Neurosurgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea


Spontaneous regression of meningioma is rarely observed. We report a one person of an incidentally diagnosed meningioma with a spontaneous regression. The 73-year-old female patient without symptoms showed the right sphenoid meningioma with peritumoral edema. The meningioma was incidentally diagnosed and followed up by MRI for 10 years. The tumor shrank with a decrease of edema on T2 MRI. The initial volume of 58.59 cm3 , regressed to 37.16 cm3 .


Meningioma; Spontaneous regression; Peritumoral edema; diabetes mellitus


  • Fig. 1 Contrast-enhanced brain MRI axial views. A: In 2012, the size of meningioma was 47.04×40.18×62.31 mm. B: 10 years later in 2022, the size of meningioma was 42.66×31.72×54.92 mm.

  • Fig. 2 T2 MRI axial views. A: MRI taken in 2012. The peritumoral edema was seen at temporal area. B: MRI taken in 2022. The peritumoral edema was almost invisible.

  • Fig. 3 Comparison of MR angiography views before and after tumor shrinkage. Yellow circle indicated the feeding arteries. A: MR angiography taken in 2012. The feeding artery was observed well. B: MR angiography taken in 2022. The feeding artery was thinly observed.


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