Ewha Med J.  1984 Mar;7(1):3-7. 10.12771/emj.1984.7.1.3.

The Effects of Vitamin A and E on Lipid Peroxidation in Ethanol Administered Rat Liver Microsomes

• Hong YS
• Ham YA
• Sung NE

• KMID: 2052611
• DOI: http://doi.org/10.12771/emj.1984.7.1.3

Abstract

Ethanol enhances the activity of microsomal enzyme system and lipid peroxidation. We observed the effect of chronic ethanol administration on cytochrome P-450 level and lipid peroxidation in rat liver microsome. The results were as follows : 1) When rats were administered with ethanol, the level of microsomal cytochrome P-450 was decreased and lipid peroxidation did not change significantly. 2) When vitamin A and E were added incubation medium in each group, lipid per-oxidation was decreased significantly.

MeSH Terms

Animals
Cytochrome P-450 Enzyme System
Ethanol*
Lipid Peroxidation*
Liver*
Microsomes, Liver*
Rats*
Vitamin A*
Vitamins*
Cytochrome P-450 Enzyme System
Ethanol
Vitamin A
Vitamins