J Korean Pain Soc.  1997 Nov;10(2):191-195.

A Comparison of Fentanyl and Bupivacaine as an Adjuvant of Epidural Morphine for Postcesarean Section Analgesia

• An SY
• Son Y
• Cheong YP
• Yun JS

Abstract

Backgound: The present study was undertaken to determine whether fentanyl or bupivacaine is a better adjuvant to epidural morphine with respect to postoperative analgesic use and with fewer incidence of side effects.
METHODS
We evaluated the clinical effects in 62 patients having cesarean section, divided in 3groups randomly. Group I (n 19) was received epidural marphine 4 mg, group II (n=22) was received epidural morphine 2 mg plus fentanyl 50 microgram and group III (n=21) was received morphine 2 mg plus 0.25% bupivacaine 10 ml epidurally. We measured the first request time of analgesic for postoperative pain, the number of supplemental analgesics within 24 hours and the incidence of side effects postoperatively.
RESULTS
The first request time of analgesic for postoperative pain was significantly shorter in group III than in group I and IL The analgesic use in the first 24 hours was significantly more in group III than in group I and II. The side effects were significantly fewer incidence in group II than in group I and III.
CONCLUSIONS
In conclusion, the combined use of epidural morphine and fentanyl provided better analgesia than the combined of epidural morphine and bupivacaine.

Keyword

Epidural analgesics, bupivacaine, fentanyl, morphine; Postoperative analgesia

MeSH Terms

Analgesia*
Analgesics
Bupivacaine*
Cesarean Section*
Female
Fentanyl*
Humans
Incidence
Morphine*
Pain, Postoperative
Pregnancy
Analgesics
Bupivacaine
Fentanyl
Morphine