Korean J Anesthesiol.  1994 Apr;27(4):388-395. 10.4097/kjae.1994.27.4.388.

Effects of Adding of Fentanyl or Morphine to Bupivacaine for the Epidural Anesthesia in the Cesarean Section

• Ko H
• Choe IH

• KMID: 2236965
• DOI: http://doi.org/10.4097/kjae.1994.27.4.388

Abstract

The effects of adding 50 ug fentanyl or 3 mg morphine to 0,5% bupivacaine for the epidural anesthesia in cesrean section were evaluated. The 59 women for elective cesarean section were randomly allocated into 3 groups. The first group (n=15) was administered epidurally with 0,5% bupivacaine alone, the second group (n=18), 0.5% bupivacaine mixed with 50 ug fentanyl, and the third group (n=l6), 0.5% bupivacaine mixed with 3 mg morphine. No significant differences among the groups were noted in systolic and diastolic blood pressure, heart rate, respiratiory rate, and tidal volume. There were no significant differences among the groups in the incidence of adverse effects (nausea, vomiting, dizziness, hypotension, pruritus, urinary retention, respiratory depression) in the perianesthetic period and in the onset time of anesthesia up to T4 sensory dermatome. Durations of the anesthesia and postoperative analgesia are prolonged significantly in the second and third groups compared with the first. We found no differences in the neonatal outcome among the groups. Therefore, we conclude that the addition of 50 ug fentanyl or 3 mg morphine to 0.5% bupivacaine during epidural anesthesia for the cesarean section significantly prolongs the duration of anesthesia and postoperative analgesia with no deleterious effects on neonatal or maternal outcome.

Keyword

Epidural anesthesia; Cesarean section; 0.5% Bupivacaine; Fentanyl; Morphine

MeSH Terms

Analgesia
Anesthesia
Anesthesia, Epidural*
Blood Pressure
Bupivacaine*
Cesarean Section*
Dizziness
Female
Fentanyl*
Heart Rate
Humans
Hypotension
Incidence
Morphine*
Pregnancy
Pruritus
Tidal Volume
Urinary Retention
Vomiting
Bupivacaine
Fentanyl
Morphine