Korean J Gastrointest Endosc.  1997 Dec;17(6):841-846.

A Case of Mesenteric Thrombosis and Partal Hypertension Associated with Antiphospholipid in a Patient with Hepatitis C

• Lee JH
• Jung SM
• Choi JH
• Oh SW
• Na BG
• Park SM
• Yun SJ
• Park KS

Abstract

The gastrointestinal rnanifestations associated with antiphospholipid antibodies include Budd-Chiari syndroame, hepatic infarction, portal hypertension, pancreatitis, intestinal infarction, perforation, bleeding and ulceration. A 40-year old man, without prior thrombotic event, presented with severe abdominal pain for 3 days and septic shock. Multiple mesenteric venous thrombosis and colonic congestion were suggested by abdominal CT and angiography. Gastroendoscopy revealed esophageal varix and congestive gastropathy. Laboratory tests disclosed postive antiphospholipid antibodies, anti-HCV antibodies, HCV-PCR, prolonged PT, aPTT, thrombocytopenia and had no evidences of SLE and other connective tissue diseases. He was diagnosed as mutiple mesenteric thrombosis and portal hypertension associated with antiphospholipid antibodies in hepatitis C virus infection. He was improved with the antibiotics and intravenous vasopressors. He have had no other thrombotic events until one year after discharge.

Keyword

Antiphospholipid antibodies; Mesenteric thrombosis; Portal hypertension; Hepatitis C

MeSH Terms

Abdominal Pain
Adult
Angiography
Anti-Bacterial Agents
Antibodies, Antiphospholipid
Colon
Connective Tissue Diseases
Esophageal and Gastric Varices
Estrogens, Conjugated (USP)
Hemorrhage
Hepacivirus
Hepatitis C Antibodies
Hepatitis C*
Hepatitis*
Humans
Hypertension*
Hypertension, Portal
Infarction
Pancreatitis
Shock, Septic
Thrombocytopenia
Thrombosis*
Tomography, X-Ray Computed
Ulcer
Venous Thrombosis
Anti-Bacterial Agents
Antibodies, Antiphospholipid
Estrogens, Conjugated (USP)
Hepatitis C Antibodies